Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity

W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

Indolizidine and quinolizidine alkaloids

JP Michael - Natural Product Reports, 2008 - pubs.rsc.org
Covering: July 2005 to June 2006. Previous review: Nat. Prod. Rep., 2007, 24, 191–222This
review covers the isolation, structure determination, synthesis, chemical transformations and …

Phenanthrene synthesis by eosin Y‐catalyzed, visible light‐induced [4+ 2] benzannulation of biaryldiazonium salts with alkynes

T Xiao, X Dong, Y Tang, L Zhou - Advanced Synthesis & …, 2012 - Wiley Online Library
A metal‐free, visible light‐induced [4+ 2] benzannulation of biaryldiazonium salts with
alkynes was developed. With eosin Y as photoredox catalyst, a variety of 9‐substituted or 9 …

Phenanthroindolizidines and phenanthroquinolizidines: promising alkaloids for anti-cancer therapy

SR Chemler - Current bioactive compounds, 2009 - ingentaconnect.com
The phenanthroindolizidine and phenanthroquinolizidine alkaloids, typified by tylophorine
and cryptopleurine, are a family of plant-derived small molecules with significant therapeutic …

Mechanochemical activation of aryl diazonium salts: Synthesis of polycyclic (hetero) aromatics

P Gao, X Wu, D Zhang, X Sun, G Zhang… - The Journal of Organic …, 2024 - ACS Publications
Although the synthesis of polycyclic (hetero) aromatics via the [4+ 2] benzannulation process
has been thoroughly explored, the restricted availability of energy sources (including …

Synthesis of Substituted Phenanthrene by Iron (III)-Catalyzed Intramolecular Alkyne–Carbonyl Metathesis

K Bera, S Sarkar, S Jalal, U Jana - The Journal of Organic …, 2012 - ACS Publications
An efficient synthesis of functionalized phenanthrenes has been developed for the first time
involving an iron (III)-catalyzed intramolecular coupling of 2′-alkynyl-biphenyl-2 …

4, 5-Diaryl-1H-pyrrole-2-carboxylates as combretastatin A-4/lamellarin T hybrids: Synthesis and evaluation as anti-mitotic and cytotoxic agents

MG Banwell, E Hamel, DCR Hockless… - Bioorganic & medicinal …, 2006 - Elsevier
The 4, 5-diarylated-1H-pyrrole-2-carboxylates 3–8 have each been prepared as hybrids of
the potent anti-mitotic agent combretastatin A-4 (1) and the similarly active marine alkaloid …

Synthesis and structure–activity studies of antofine analogues as potential anticancer agents

Y Fu, SK Lee, HY Min, T Lee, J Lee, M Cheng… - Bioorganic & Medicinal …, 2007 - Elsevier
Due to the profound cytotoxicities and interesting biochemical aspects,
phenanthroindolizidine alkaloids have received an attention as potential therapeutic leads …

Expeditious Synthesis of Phenanthrenes via CuBr2-Catalyzed Coupling of Terminal Alkynes and N-Tosylhydrazones Derived from O-Formyl Biphenyls

F Ye, Y Shi, L Zhou, Q Xiao, Y Zhang, J Wang - Organic Letters, 2011 - ACS Publications
A new method for the synthesis of phenanthrenes via ligand-free CuBr2-catalyzed
coupling/cyclization of terminal alkynes with N-tosylhydrazones derived from o-formyl …

Catalyst-Free Intramolecular Formal Carbon Insertion into σ-C C Bonds: A New Approach toward Phenanthrols and Naphthols.

Y Xia, P Qu, Z Liu, R Ge, Q Xiao… - Angewandte Chemie …, 2013 - search.ebscohost.com
The different reactivity of two kinds of carbonyl groups in keto aldehyde substrates has been
exploited for the synthesis of phenanthrols, naphthols, and their heteroatom‐containing …