Cadmium (Cd) is a toxic heavy metal that targets the kidney directly in the body. Chrysin
(CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and …

Fruits and vegetables serve not only as sources of nutrition but also as medicinal agents for
the treatment of diverse diseases and maladies. These dietary components are significant …

Background Side effects of cisplatin (CIS) such as testicular toxicity restrict its clinical use.
Instead, evidence indicates that crocin (CR) has synergistic anti-cancer potential with CIS …

Sonchus cornutus (Asteraceae) is a wild. edible plant that represents a plentiful source of
polyphenolic compounds. For the first time, the metabolic analysis profiling demonstrated …

Abstract Background Cadmium (Cd) is a strong toxic agent and causes serious damage to
testicular tissues. Chrysin (CHR) is a natural flavonoid with many effective properties …

Renal tubulointerstitial fibrosis (RIF), featured by epithelial-to-mesenchymal-transition (EMT)
of renal tubular epithelial cells and collagen deposition in the renal interstitial region, is the …

Significance: Drug-induced liver injury (DILI) or hepatotoxicity has been a hot issue to
overcome on the safety and physiological function of the liver, since it is known to have …

Background Alpinia officinarum is a member of the ginger family (Zingiberaceae), which is
widely cultivated in Asia and traditionally used for its anti-inflammatory, antimicrobial, and …

Doxorubicin belongs to the class of anthracycline antibiotics that is widely used in the
treatment protocols of a wide range of malignancies. The major deleterious effect of …

Background. Cytokine storm syndrome (CSS) is a major cause of morbidity and mortality in
people suffering from hyperinflammatory status, which diverse etiological factors, including …