[PDF][PDF] Immunosuppression in pediatric liver transplant recipients: unique aspects

T Miloh, A Barton, J Wheeler, Y Pham… - Liver …, 2017 - Wiley Online Library
Pediatric liver transplantation has experienced improved outcomes over the last 50 years.
This can be attributed in part to establishing optimal use of immunosuppressive agents to …

Paediatric use of mycophenolate mofetil

HJ Downing, M Pirmohamed… - British journal of …, 2013 - Wiley Online Library
A number of medications do not have a licence, or label, for use in the paediatric age group
nor for the specific indication for which they are being used in children. Over recent years …

Pharmacokinetics and pharmacodynamics of mycophenolic acid and their relation to response to therapy of childhood-onset systemic lupus erythematosus

ACP Sagcal-Gironella, T Fukuda, K Wiers, S Cox… - Seminars in arthritis and …, 2011 - Elsevier
OBJECTIVES: Mycophenolic acid (MPA) is the active form of mycophenolate mofetil (MMF),
which is currently used off-label as immunosuppressive therapy in childhood-onset SLE …

Postoperative care in pediatric liver transplantation

U Tannuri, ACA Tannuri - Clinics, 2014 - SciELO Brasil
In the last 25 years, liver transplantation in children has become an effective, definitive, and
universally accepted treatment for terminal liver diseases. Long-term survival exceeds 80 …

[PDF][PDF] High burden of subclinical cardiovascular target organ damage after pediatric liver transplantation

N Memaran, B Borchert‐Mörlins… - Liver …, 2019 - Wiley Online Library
Cardiovascular (CV) events account for 8%‐13% of deaths after liver transplantation (LT) in
adulthood. Although CV risk factors (RFs) are present, little is known about the prevalence of …

[HTML][HTML] The adolescent and liver transplantation

P Burra - Journal of hepatology, 2012 - Elsevier
The outcome of liver transplantation is usually reported in terms of graft and patient survival,
medical and surgical complications, and quality of life, but when it comes to transplanted …

Current concepts in pediatric liver transplantation

S Emre, V Umman, B Cimsit… - Mount Sinai Journal of …, 2012 - Wiley Online Library
Liver transplantation is the definitive treatment for end‐stage liver disease in both children
and adults. Advances over the last 2 decades have resulted in excellent patient and graft …

Renal dysfunction in the perioperative liver transplant period

G Biancofiore, CL Davis - Current Opinion in Organ …, 2008 - journals.lww.com
Renal dysfunction in the perioperative liver transplant peri... : Current Opinion in Organ
Transplantation Renal dysfunction in the perioperative liver transplant period : Current Opinion …

Calcineurin-inhibitor minimization in liver transplant patients with calcineurin-inhibitor-related renal dysfunction: a meta-analysis

Y Kong, D Wang, Y Shang, W Liang, X Ling, Z Guo… - PLoS …, 2011 - journals.plos.org
Background Introduction of calcineurin-inhibitor (CNI) has made transplantation a miracle in
the past century. However, the side effects of long-term use of CNI turn out to be one of the …

[HTML][HTML] Mycophenolate mofetil and calcineurin-inhibitor reduction: recent progress

JM Grinyó, JM Cruzado - American Journal of Transplantation, 2009 - Elsevier
Mycophenolate mofetil (MMF) in combination with calcineurin inhibitors (CNIs) has greatly
contributed to acute rejection rate reduction. Because of its immunosuppressive potency it …