Molecular mechanism of down-regulating adipogenic transcription factors in 3T3-L1 adipocyte cells by bioactive anti-adipogenic compounds

A Guru, PK Issac, M Velayutham, NT Saraswathi… - Molecular Biology …, 2021 - Springer
Obesity is growing at an alarming rate, which is characterized by increased adipose tissue. It
increases the probability of many health complications, such as diabetes, arthritis, cardiac …

Therapeutic potential of PPARγ natural agonists in liver diseases

L Wu, C Guo, J Wu - Journal of cellular and molecular …, 2020 - Wiley Online Library
Peroxisome proliferator‐activated receptor gamma (PPARγ) is a vital subtype of the PPAR
family. The biological functions are complex and diverse. PPARγ plays a significant role in …

Medicinal plants utilized in Thai Traditional Medicine for diabetes treatment: Ethnobotanical surveys, scientific evidence and phytochemicals

C Andrade, NGM Gomes, S Duangsrisai… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Diabetes mellitus remains the most lethal metabolic
disease of contemporaneous times and despite the therapeutic arsenal currently available …

Plants of the Genus Terminalia: An Insight on Its Biological Potentials, Pre-Clinical and Clinical Studies

G Das, DY Kim, C Fan, EP Gutiérrez-Grijalva… - Frontiers in …, 2020 - frontiersin.org
The evaluation and confirmation of healing properties of several plant species of genus
Terminalia based on their traditional uses and the clinical claims are of utmost importance …

Phytochemical profile and pro-healthy properties of Terminalia chebula: A comprehensive review

MT Sultan, MJ Anwar, M Imran, I Khalil… - … Journal of Food …, 2023 - Taylor & Francis
Globalization witnessed changing trends in consumer markets. However, their long-term
impacts include lifestyle and dietary changes. Although research in the pharmaceutical and …

Isolated compounds from natural products with potential antidiabetic activity-a systematic review

ACM Munhoz, TS Frode - Current diabetes reviews, 2018 - benthamdirect.com
Background: Worldwide, Type 2 diabetes has become a growing health problem. While
many research articles in the field of ethnopharmacology have focused on the antidiabetic …

Phloretin and phloridzin improve insulin sensitivity and enhance glucose uptake by subverting PPARγ/Cdk5 interaction in differentiated adipocytes

S Kumar, K Sinha, R Sharma, R Purohit… - Experimental cell …, 2019 - Elsevier
Activators of peroxisome proliferator-activated receptor-γ (PPARγ agonists) are
therapeutically promising candidates against insulin resistance and hyperglycemia …

A Comprehensive Review of the Structure Elucidation of Tannins from Terminalia Linn.

Z Chang, Q Zhang, W Liang, K Zhou… - Evidence‐Based …, 2019 - Wiley Online Library
Objectives. Tannins with complex structures are important plant resources, which are
abundant in the genus Terminalia. Various Terminalia species have been playing an …

Picrorhiza kurroa Enhances β-Cell Mass Proliferation and Insulin Secretion in Streptozotocin Evoked β-Cell Damage in Rats

S Kumar, V Patial, S Soni, S Sharma… - Frontiers in …, 2017 - frontiersin.org
Autoimmune destruction of insulin producing pancreatic β-cells leads to insulin insufficiency
and hyperglycemia in type 1 diabetes mellitus. Regeneration of β-cells is one of the …

[HTML][HTML] Revealing the potential hypoglycaemic ingredients of Terminalia chebula Retz. by spectrum–effect relationship combining molecular docking and …

Y Yan, R Abdulla, X Xin, HA Aisa - Journal of Functional Foods, 2024 - Elsevier
Terminalia chebula Retz. is commonly used in the treatment of diabetes, but its specific
ingredients and hypoglycaemic mechanisms remain unclear. In this study, spectrum-effect …