International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function

NM Barnes, GP Ahern, C Becamel, J Bockaert… - Pharmacological …, 2021 - Elsevier
HT receptors expressed throughout the human body are targets for established therapeutics
and various drugs in development. Their diversity of structure and function reflects the …

The role of serotonin neurotransmission in gastrointestinal tract and pharmacotherapy

T Guzel, D Mirowska-Guzel - Molecules, 2022 - mdpi.com
5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous
system and peripheral structures, acting also as a hormone in platelets. Although its …

[HTML][HTML] Gene expression profiling in hepatocellular carcinoma: upregulation of genes in amplified chromosome regions

B Skawran, D Steinemann, A Weigmann, P Flemming… - Modern Pathology, 2008 - Elsevier
Cytogenetics of hepatocellular carcinoma and adenoma have revealed gains of
chromosome 1q as a significant differentiating factor. However, no studies are available …

[HTML][HTML] Growth rate of early-stage hepatocellular carcinoma in patients with chronic liver disease

C An, YA Choi, D Choi, YH Paik, SH Ahn… - Clinical and …, 2015 - ncbi.nlm.nih.gov
Methods Patients with early-stage HCC (n= 175) who underwent two or more serial dynamic
imaging studies without any anticancer treatment at two tertiary care hospitals in Korea were …

New therapeutic opportunities for 5-HT2 receptor ligands

L Maroteaux, E Ayme-Dietrich, G Aubertin-Kirch… - Pharmacology & …, 2017 - Elsevier
Serotonergic dysfunction is mainly associated with neuropsychiatric and cardiovascular
disorders but has also been linked with many other pathological conditions. Serotonin (5 …

Identification of a novel eight‐lncRNA prognostic signature for HBV‐HCC and analysis of their functions based on coexpression and ceRNA networks

X Zhao, Z Bai, C Li, C Sheng… - BioMed Research …, 2020 - Wiley Online Library
Studies have demonstrated the prognosis potential of long noncoding RNAs (lncRNAs) for
hepatocellular carcinoma (HCC), but specific lncRNAs for hepatitis B virus‐(HBV‐) related …

Gene expression profiling of human HBV-and/or HCV-associated hepatocellular carcinoma cells using expressed sequence tags

SY Yoon, JM Kim, JH Oh, YJ Jeon… - International …, 2006 - spandidos-publications.com
Liver cancer is one of the leading causes of cancer death worldwide. To identify novel target
genes that are related to liver carcinogenesis, we examined new genes that are differentially …

Effect of the etiology of viral cirrhosis on the survival of patients with hepatocellular carcinoma

MC Cantarini, F Trevisani… - Official journal of the …, 2006 - journals.lww.com
OBJECTIVES The aim of this study was to assess whether hepatocellular carcinoma
occurring in the setting of hepatitis B or C virus infection has different prognosis. METHODS …

[HTML][HTML] Up-regulation of NAD (P) H quinone oxidoreductase 1 during human liver injury

LM Aleksunes, M Goedken… - World journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To investigate the expression and activity of NAD (P) H quinone oxidoreductase 1
(NQO1) in human liver specimens obtained from patients with liver damage due to …

Cell cycle regulation and hepatocarcinogenesis

LE Greenbaum - Cancer biology & therapy, 2004 - Taylor & Francis
Hepatocellular carcinoma (HCC) develops on a background of chronic hepatitis or cirrhosis.
The slow progression of this disease has facilitated the identification of discrete pathologic …