Advances over the past 25 years have revealed much about how the structural properties of
membranes and associated proteins are linked to the thermodynamics and kinetics of …

Although the anionic surfactant sodium dodecyl sulfate, SDS, has been used for more than
half a century as a versatile and efficient protein denaturant for protein separation and size …

Long-range distance measurements based on paramagnetic relaxation enhancement (PRE)
in NMR, quantification of surface water dynamics near biomacromolecules by Overhauser …

To import large metabolites across the outer membrane of gram-negative bacteria, TonB-
dependent transporters (TBDTs) undergo significant conformational change. After substrate …

The β2 adrenergic receptor (β2AR) is an archetypal G protein coupled receptor (GPCR).
One structural signature of GPCR activation is a large-scale movement (ca. 6 to 14 Å) of …

Protein folding is a fundamental process of life with important implications throughout
biology. Indeed, tens of thousands of mutations have been associated with diseases, and …

As a result of their unique physical properties, biological membrane mimetics, such as
liposomes, are used in a broad range of scientific and technological applications …

Membrane proteins evolved to reside in the hydrophobic lipid bilayers of cellular
membranes. Therefore, membrane proteins bridge the different aqueous compartments …

The strong and usually denaturing interaction between anionic surfactants (AS) and
proteins/enzymes has both benefits and drawbacks: for example, it is put to good use in …

The intricate functions of membrane proteins would not be possible without bends or breaks
that are remarkably common in transmembrane helices. The frequent helix distortions are …