Autoimmunity may be generated by a variety of factors by creating a hyper-stimulated state
of the immune system. It had been established long ago that viruses are a substantial …

Follicular helper T (TFH) cells provide help to B cells, supporting the formation of germinal
centres that allow affinity maturation of antibody responses. Although usually located in …

Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse
symptoms, which can persist for months. While antiviral antibodies are protective, those …

Background Activation of the immune system is implicated in the Post-Acute Sequelae after
SARS-CoV-2 infection (PASC) but the mechanisms remain unknown. Angiotensin …

Background COVID-19 intensive care patients can present with neurological syndromes,
usually in the absence of SARS-CoV-2 in cerebrospinal fluid (CSF). The recent finding of …

Multisystem inflammatory syndrome in children (MIS-C) manifests as a severe and
uncontrolled inflammatory response with multiorgan involvement, occurring weeks after …

A 52-year-old man presented to the emergency department≈ 90 min after the onset of
substernal chest pain. Three days before presentation, he received his second dose of …

Autism is a neurodevelopmental disorder characterized by deficits in communication and
social skills as well as repetitive and stereotypical behaviors. While much effort has focused …

Autoimmune diseases (AID) are increasingly prevalent conditions which comprise more
than 100 distinct clinical entities that are responsible for a great disease burden worldwide …

Neutrophils are best known for their critical role in host defense, for which they utilize
multiple innate immune mechanisms, including microbe-associated pattern recognition …