Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small
group or even individual patients based on their genetics, environment and lifestyle …

Abstract Metabolic Syndrome (MetS) is a highly heritable disease and a major public health
burden worldwide. MetS diagnosis criteria is met by the simultaneous presence of any three …

Despite the crucial roles of lipids in metabolism, we are still at the early stages of
comprehensively annotating lipid species and their genetic basis. Mass spectrometry–based …

Heterogeneous Stock (HS) rats are a genetically diverse outbred rat population that is
widely used for studying genetics of behavioral and physiological traits. Mapping …

Purpose: Lipid metabolism reprogramming is a major pathway in tumor evolution. This study
investigated fatty acid synthase (FASN) mRNA expression in anthropometric adipose tissue …

В обзоре представлены возможности применения искусственного интеллекта для
изучения механизмов развития сахарного диабета (СД) и создания новых технологий …

Multi-omics approaches use a diversity of high-throughput technologies to profile the
different molecular layers of living cells. Ideally, the integration of this information should …

How effects of DNA sequence variants are transmitted through intermediate
endophenotypes to modulate organismal traits remains a central question in quantitative …

This review presents the applications of artificial intelligence for the study of the mechanisms
of diabetes development and generation of new technologies of its prevention, monitoring …

Background This research aimed at exploring the mechanisms of alterations of metabolites
and pathways in T2D from the perspective of metabolomics and transcriptomics, as well as …