The current global pandemic COVID-19 caused by the SARS-CoV-2 virus has already
inflicted insurmountable damage both to the human lives and global economy. There is an …

Artificial intelligence (AI) is a machine science that can mimic human behaviour like
intelligent analysis of data. AI functions with specialized algorithms and integrates with deep …

Rheumatoid arthritis (RA) remains one of the most prevalent autoimmune diseases
worldwide. Janus kinase 3 (JAK3) is an essential enzyme for treating autoimmune diseases …

Genomic resources for Platyhelminthes of the class Monogenea are scarce, despite the
diversity of these parasites, some species of which are highly pathogenic to their fish hosts …

How can biophysical principles help precision medicine identify rare driver mutations? A
major tenet of pragmatic approaches to precision oncology and pharmacology is that driver …

α-galactosidase (α-GAL) and α-N-acetylgalactosaminidase (α-NAGAL) are two glycosyl
hydrolases responsible for maintaining cellular homeostasis by regulating glycan substrates …

Schistosomiasis is a neglected tropical disease affecting more than 200 million people
worldwide. Chemotherapy relies on one single drug, praziquantel, which is safe but …

A delicate balance between programmed cell death and proliferation of intestinal epithelial
cells (IEC) exists in the gut to maintain homeostasis. Homeostatic cell death programs such …

Introduction: Exploring the potential efficacy of a drug is a valid approach for drug
development with shorter development times and lower costs. Recently, several …

Schistosomiasis is a parasitic disease caused by trematode worms of the genus
Schistosoma and affects over 200 million people worldwide. The control and treatment of …