A guide to conquer the biological network era using graph theory

M Koutrouli, E Karatzas, D Paez-Espino… - … in bioengineering and …, 2020 - frontiersin.org
Networks are one of the most common ways to represent biological systems as complex sets
of binary interactions or relations between different bioentities. In this article, we discuss the …

A travel guide to Cytoscape plugins

R Saito, ME Smoot, K Ono, J Ruscheinski, PL Wang… - Nature …, 2012 - nature.com
Cytoscape is open-source software for integration, visualization and analysis of biological
networks. It can be extended through Cytoscape plugins, enabling a broad community of …

The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer

G Mirji, A Worth, SA Bhat, M El Sayed, T Kannan… - Science …, 2022 - science.org
The composition of the gut microbiome can control innate and adaptive immunity and has
emerged as a key regulator of tumor growth, especially in the context of immune checkpoint …

Cytoscape StringApp: network analysis and visualization of proteomics data

NT Doncheva, JH Morris, J Gorodkin… - Journal of proteome …, 2018 - ACS Publications
Protein networks have become a popular tool for analyzing and visualizing the often long
lists of proteins or genes obtained from proteomics and other high-throughput technologies …

A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseases

MJ Tisza, CB Buck - … of the National Academy of Sciences, 2021 - National Acad Sciences
Despite remarkable strides in microbiome research, the viral component of the microbiome
has generally presented a more challenging target than the bacteriome. This gap persists …

Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS

C Guo, X Che, T Briese, A Ranjan, O Allicock… - Cell host & …, 2023 - cell.com
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by
unexplained debilitating fatigue, cognitive dysfunction, gastrointestinal disturbances, and …

Integrated proteogenomic characterization of clear cell renal cell carcinoma

DJ Clark, SM Dhanasekaran, F Petralia, J Pan, X Song… - Cell, 2019 - cell.com
To elucidate the deregulated functional modules that drive clear cell renal cell carcinoma
(ccRCC), we performed comprehensive genomic, epigenomic, transcriptomic, proteomic …

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

D Szklarczyk, JH Morris, H Cook, M Kuhn… - Nucleic acids …, 2016 - academic.oup.com
A system-wide understanding of cellular function requires knowledge of all functional
interactions between the expressed proteins. The STRING database aims to collect and …

Noninvasive assessment of gut function using transcriptional recording sentinel cells

F Schmidt, J Zimmermann, T Tanna, R Farouni… - Science, 2022 - science.org
Transcriptional recording by CRISPR spacer acquisition from RNA endows engineered
Escherichia coli with synthetic memory, which through Record-seq reveals transcriptome …

Cytoscape stringApp 2.0: analysis and visualization of heterogeneous biological networks

NT Doncheva, JH Morris, H Holze… - Journal of proteome …, 2022 - ACS Publications
Biological networks are often used to represent complex biological systems, which can
contain several types of entities. Analysis and visualization of such networks is supported by …