Bipolar disorder (BD) is a complex disorder with a range of presentations. BD is defined by
the presentation of symptoms of mania or depression, with classification dependent on …

Background Lithium is the lightest metal and the only mood stabilizer that has been used for
over half a century for the treatment of bipolar disorder (BD). As a small ion, lithium is …

The present study aims to investigate the oxidative stress parameters in isolated
mitochondria, as well as looking at mitochondrial complex activity in patients with Bipolar …

Bipolar disorder (BD) is a long-recognized severe and common psychiatric disorder, with a
complex and often diverse range of presentations. BD is a heterogenous disorder that has …

Background Anxiety, mood, trauma-and stressor-related disorders confer increased risk for
metabolic disease. Adiponectin, a cytokine released by adipose tissue is associated with …

Replicated evidence indicates that individuals with BD are differentially affected by
metabolic comorbidities and that its occurrence is a critical mediator and/or moderator of BD …

Metabolic syndrome is characterized by insulin resistance, obesity, and dyslipidemia. It is
the consequence of an imbalance between caloric intake and energy consumption …

Objectives: One of the current challenges in psychiatry is the search for answers on how to
effectively manage drug-resistant depression. The occurrence of drug resistance in patients …

Background and Objectives: There is no biomarker to predict lithium response. This study
used CellPrint™ enhanced flow cytometry to study 28 proteins representing a spectrum of …

Background Objective of the present study was to conduct an 8-week double-blind,
randomized, placebo-controlled trial to test the efficacy of pioglitazone in the treatment of …