Galectins as modulators of tumour progression

FT Liu, GA Rabinovich - Nature Reviews Cancer, 2005 - nature.com
Galectins are a family of animal lectins with diverse biological activities. They function both
extracellularly, by interacting with cell-surface and extracellular matrix glycoproteins and …

Pleiotropic effects of modified citrus pectin

I Eliaz, A Raz - Nutrients, 2019 - mdpi.com
Modified citrus pectin (MCP) has a low-molecular-weight degree of esterification to allow
absorption from the small intestinal epithelium into the circulation. MCP produces pleiotropic …

Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression

CH Chung, JS Parker, G Karaca, J Wu, WK Funkhouser… - Cancer cell, 2004 - cell.com
The prognostication of head and neck squamous cell carcinoma (HNSCC) is largely based
upon the tumor size and location and the presence of lymph node metastases. Here we …

CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis

T Fukumori, Y Takenaka, T Yoshii, HRC Kim, V Hogan… - Cancer research, 2003 - AACR
Abstract Galectin (Gal)-3, a M r 31,000 member of the β-galactoside-binding protein family,
is a multifunctional protein implicated in a variety of biological functions, including tumor cell …

Pregnancy recognition and conceptus implantation in domestic ruminants: roles of progesterone, interferons and endogenous retroviruses

TE Spencer, GA Johnson, FW Bazer… - Reproduction, fertility …, 2006 - CSIRO Publishing
The present review highlights new information on pregnancy recognition and conceptus
development and implantation in sheep with respect to regulation by progesterone …

Implantation mechanisms: insights from the sheep

TE Spencer, GA Johnson, FW Bazer… - …, 2004 - rep.bioscientifica.com
Implantation in all mammals involves shedding of the zona pellucida, followed by
orientation, apposition, attachment and adhesion of the blastocyst to the endometrium …

Modified citrus pectin anti-metastatic properties: one bullet, multiple targets

VV Glinsky, A Raz - Carbohydrate research, 2009 - Elsevier
In this minireview, we examine the ability of modified citrus pectin (MCP), a complex water
soluble indigestible polysaccharide obtained from the peel and pulp of citrus fruits and …

[HTML][HTML] A role for insect galectins in parasite survival

S Kamhawi, M Ramalho-Ortigao, VM Pham, S Kumar… - Cell, 2004 - cell.com
Insect galectins are associated with embryonic development or immunity against pathogens.
Here, we show that they can be exploited by parasites for survival in their insect hosts …

Chemical approaches to glycobiology

LL Kiessling, RA Splain - Annual review of biochemistry, 2010 - annualreviews.org
Glycans are ubiquitous components of all organisms. Efforts to elucidate glycan function and
to understand how they are assembled and disassembled can reap benefits in fields …

Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-κB signaling as characteristics of a high-risk head and neck …

CH Chung, JS Parker, K Ely, J Carter, Y Yi, BA Murphy… - Cancer research, 2006 - AACR
Gene expression signatures generated from DNA microarray analyses have shown promise
as predictive biomarkers of clinical outcome. In this study, we determined a high-risk …