[HTML][HTML] Membrane-type matrix metalloproteinases: Their functions and regulations

Y Itoh - Matrix Biology, 2015 - Elsevier
Membrane-type matrix metalloproteinases (MT-MMPs) form a subgroup of the matrix
metalloproteinase (MMP) family, and there are 6 MT-MMPs in humans. MT-MMPs are further …

New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumor progression

B Bauvois - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2012 - Elsevier
This review focuses on matrix metalloproteinases (MMPs)-2 (gelatinase A) and-9
(gelatinase B), both of which are cancer-associated, secreted, zinc-dependent …

[HTML][HTML] A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential

E Gobin, K Bagwell, J Wagner, D Mysona… - BMC cancer, 2019 - Springer
Abstract Implication By understanding Matrix Metalloprotease (MMP) dysregulation from a
pan-cancer perspective, this study sheds light on the diagnostic potentials of MMPs across …

[HTML][HTML] Matrix metalloproteinases: what do they not do? New substrates and biological roles identified by murine models and proteomics

D Rodríguez, CJ Morrison, CM Overall - Biochimica et Biophysica Acta …, 2010 - Elsevier
The biological roles of the matrix metalloproteinases (MMPs) have been traditionally
associated with the degradation and turnover of most of the components of the extracellular …

Missing the target: matrix metalloproteinase antitargets in inflammation and cancer

A Dufour, CM Overall - Trends in pharmacological sciences, 2013 - cell.com
Matrix metalloproteinases (MMPs) are reputed to cause the inflammatory tissue destruction
characterizing chronic inflammatory diseases and to degrade basement membrane …

Gelatinase-mediated migration and invasion of cancer cells

M Björklund, E Koivunen - Biochimica et Biophysica Acta (BBA)-Reviews …, 2005 - Elsevier
The matrix metalloproteinases (MMP)-2 and-9, also known as the gelatinases have been
long recognized as major contributors to the proteolytic degradation of extracellular matrix …

A novel angiotensin-converting enzyme (ACE) inhibitory peptide from tilapia skin: Preparation, identification and its potential antihypertensive mechanism

Y Dong, W Yan, YQ Zhang, ZY Dai - Food Chemistry, 2024 - Elsevier
To obtain food-derived peptides with high ACE inhibitory activity, tilapia skin was pretreated
with steam explosion prior to enzymatic hydrolysis. The results showed that steam explosion …

[HTML][HTML] Gelatinase B/MMP-9 in tumour pathogenesis and progression

AR Farina, AR Mackay - Cancers, 2014 - mdpi.com
Since its original identification as a leukocyte gelatinase/type V collagenase and tumour
type IV collagenase, gelatinase B/matrix metalloproteinase (MMP)-9 is now recognised as …

Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts

M Bilban, N Ghaffari-Tabrizi… - Journal of cell …, 2004 - journals.biologists.com
Trophoblast invasion of the uterine extracellular matrix, a critical process of human
implantation and essential for fetal development, is a striking example of controlled …

Human matrix metalloproteinases: an ubiquitarian class of enzymes involved in several pathological processes

D Sbardella, GF Fasciglione, M Gioia, C Ciaccio… - Molecular aspects of …, 2012 - Elsevier
Human matrix metalloproteinases (MMPs) belong to the M10 family of the MA clan of
endopeptidases. They are ubiquitarian enzymes, structurally characterized by an active site …