Potential in vivo roles of nucleic acid triple-helices
The ability of double-stranded DNA to form a triple-helical structure by hydrogen bonding
with a third strand is well established, but the biological functions of these structures remain …
with a third strand is well established, but the biological functions of these structures remain …
Targeting Non‐B‐Form DNA in Living Cells
Y Du, X Zhou - The Chemical Record, 2013 - Wiley Online Library
Under certain conditions, repetitive DNA motifs have the potential to adopt non‐B‐form DNA
structures, such as hairpins, triplexes, Z‐DNA, quadruplexes, and i‐motifs. Some non‐B …
structures, such as hairpins, triplexes, Z‐DNA, quadruplexes, and i‐motifs. Some non‐B …
Halloysite nanotubes-carbon dots hybrids multifunctional nanocarrier with positive cell target ability as a potential non-viral vector for oral gene therapy
M Massaro, G Barone, G Biddeci, G Cavallaro… - Journal of colloid and …, 2019 - Elsevier
Hypothesis The use of non-viral vectors for gene therapy is hindered by their lower
transfection efficiency and their lacking of self-track ability. Experiments This study aims to …
transfection efficiency and their lacking of self-track ability. Experiments This study aims to …
Recognition of RNA duplexes by chemically modified triplex-forming oligonucleotides
Y Zhou, E Kierzek, ZP Loo, M Antonio… - Nucleic acids …, 2013 - academic.oup.com
Triplex is emerging as an important RNA tertiary structure motif, in which consecutive non-
canonical base pairs form between a duplex and a third strand. RNA duplex region is also …
canonical base pairs form between a duplex and a third strand. RNA duplex region is also …
Reversible circularization of an anthracene-modified DNA conjugate through bimolecular triplex formation and its analytical application
P Arslan, A Jyo, T Ihara - Organic & Biomolecular Chemistry, 2010 - pubs.rsc.org
We prepared an oligodeoxyribonucleotide conjugate (5-3ant218) carrying two anthracenes,
each of which was tethered to both ends of the conjugate through hexamethylene linker …
each of which was tethered to both ends of the conjugate through hexamethylene linker …
DNA complexes containing joined triplex and duplex motifs: melting behavior of intramolecular and bimolecular complexes with similar sequences
HT Lee, I Khutsishvili, LA Marky - The Journal of Physical …, 2010 - ACS Publications
Our laboratory is interested in predicting the thermal stability and melting behavior of nucleic
acids from knowledge of their sequence. One focus is to understand how sequence, duplex …
acids from knowledge of their sequence. One focus is to understand how sequence, duplex …
Effect of dC→ d (m5C) substitutions on the folding of intramolecular triplexes with mixed TAT and C+ GC base triplets
CE Carr, R Ganugula, R Shikiya, AM Soto, LA Marky - Biochimie, 2018 - Elsevier
Oligonucleotide-directed triple helix formation has been recognized as a potential tool for
targeting genes with high specificity. Cystosine methylation in the 5′ position is both …
targeting genes with high specificity. Cystosine methylation in the 5′ position is both …
Design and characterization of pH-triggered DNA nanoswitches and nanodevices based on DNA triplex structures
Triplex DNA is becoming a very useful domain to design pH-triggered DNA nanoswitches
and nanodevices. The high versatility and programmability of triplex DNA interactions allows …
and nanodevices. The high versatility and programmability of triplex DNA interactions allows …
Unfolding thermodynamics of DNA intramolecular complexes involving joined triple-and double-helical motifs
I Khutsishvili, S Johnson, HT Lee, LA Marky - Methods in enzymology, 2009 - Elsevier
Our laboratory is interested in predicting the thermal stability and melting behavior of nucleic
acids from knowledge of their sequence. One focus is to understand how sequence, duplex …
acids from knowledge of their sequence. One focus is to understand how sequence, duplex …
Effect of loop length and sequence on the stability of DNA pyrimidine triplexes with TAT base triplets
HT Lee, CE Carr, I Khutsishvili… - The Journal of Physical …, 2017 - ACS Publications
We report the thermodynamic contributions of loop length and loop sequence to the overall
stability of DNA intramolecular pyrimidine triplexes. Two sets of triplexes were designed: in …
stability of DNA intramolecular pyrimidine triplexes. Two sets of triplexes were designed: in …