Fractal characteristics of chromatin, revealed by light or electron microscopy, have been
reported during the last 20 years. Fractal features can easily be estimated in digitalized …

Introduction: Fractality is omnipresent in medicine and life sciences. In particular, the fractal
principle is found simultaneously at different organization levels of the cell nucleus. The aim …

Transposable elements constitute about half of human genomes, and their role in
generating human variation through retrotransposition is broadly studied and appreciated …

DNA methylation is a key epigenetic modification which, in mammals, occurs mainly at CpG
dinucleotides. Most of the CpG methylation in the genome is found in repetitive regions, rich …

Abstract Background Short tandem repeats (STRs) compose approximately 3% of the
genome, and mutations at STR loci have been linked to dozens of human diseases …

Transposable elements (TEs) comprise a substantial portion of eukaryotic genomes. They
have the unique ability to integrate into new locations and serve as the main source of …

Background: We evaluated the clinical prognostic value of methylation of two non-coding
repeat sequences, long interspersed element 1 (LINE-1) and Alu, in rectal tumour tissues. In …

Background Alu elements are the most abundant retrotransposable elements comprising~
11% of the human genome. Many studies have highlighted the role that Alu elements have …

Endocrine disrupting chemicals (EDCs) set a public health risk through disruption of normal
physiological processes. The toxicoepigenetic mechanisms of developmental exposure to …

The objectives of this study were to determine if global DNA methylation, as reflected in LINE‐
1 and Alu elements, is associated with telomere length and whether it modifies the rate of …