Neuronal and extraneuronal nicotinic acetylcholine receptors
Neuronal nicotinic acetylcholine receptors (nAChRs) belong to a super-family of Cysloop
ligand-gated ion channels that respond to endogenous acetylcholine (ACh) or other …
ligand-gated ion channels that respond to endogenous acetylcholine (ACh) or other …
The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms
BG Fry, K Roelants, DE Champagne… - Annual review of …, 2009 - annualreviews.org
Throughout evolution, numerous proteins have been convergently recruited into the venoms
of various animals, including centipedes, cephalopods, cone snails, fish, insects (several …
of various animals, including centipedes, cephalopods, cone snails, fish, insects (several …
Nicotinic acetylcholine receptors: from structure to brain function
RC Hogg, M Raggenbass, D Bertrand - Reviews of physiology …, 2003 - Springer
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels and can be
divided into two groups: muscle receptors, which are found at the skeletal neuromuscular …
divided into two groups: muscle receptors, which are found at the skeletal neuromuscular …
Lynx1, a cholinergic brake, limits plasticity in adult visual cortex
Experience-dependent brain plasticity typically declines after an early critical period during
which circuits are established. Loss of plasticity with closure of the critical period limits …
which circuits are established. Loss of plasticity with closure of the critical period limits …
From genome to “venome”: molecular origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences and related body …
BG Fry - Genome research, 2005 - genome.cshlp.org
This study analyzed the origin and evolution of snake venom proteome by means of
phylogenetic analysis of the amino acid sequences of the toxins and related nonvenom …
phylogenetic analysis of the amino acid sequences of the toxins and related nonvenom …
The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function
ML Sinkus, S Graw, R Freedman, RG Ross… - …, 2015 - Elsevier
The human α7 neuronal nicotinic acetylcholine receptor gene (CHRNA7) is ubiquitously
expressed in both the central nervous system and in the periphery. CHRNA7 is genetically …
expressed in both the central nervous system and in the periphery. CHRNA7 is genetically …
Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations
DK Williams, J Wang, RL Papke - Biochemical pharmacology, 2011 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChR), recognized targets for drug
development in cognitive and neuro-degenerative disorders, are allosteric proteins with …
development in cognitive and neuro-degenerative disorders, are allosteric proteins with …
GABAA receptors and plasticity of inhibitory neurotransmission in the central nervous system
JM Fritschy, P Panzanelli - European Journal of Neuroscience, 2014 - Wiley Online Library
GABAA receptors (GABAAR s) are ligand‐gated Cl− channels that mediate most of the fast
inhibitory neurotransmission in the central nervous system (CNS). Multiple GABAAR …
inhibitory neurotransmission in the central nervous system (CNS). Multiple GABAAR …
Cys-loop receptors: new twists and turns
HA Lester, MI Dibas, DS Dahan, JF Leite… - Trends in …, 2004 - cell.com
New hypotheses and predictions have arisen from recent work revealing atomic-scale or
near-atomic-scale structures of receptors in the 'Cys-loop'superfamily. How general is the …
near-atomic-scale structures of receptors in the 'Cys-loop'superfamily. How general is the …
Cerebellum: development and medulloblastoma
MF Roussel, ME Hatten - Current topics in developmental biology, 2011 - Elsevier
In the last 20 years, it has become clear that developmental genes and their regulators,
noncoding RNAs including microRNAs and long-noncoding RNAs, within signaling …
noncoding RNAs including microRNAs and long-noncoding RNAs, within signaling …