[HTML][HTML] Hepatic ischemia reperfusion injury: A systematic review of literature and the role of current drugs and biomarkers

M Cannistrà, M Ruggiero, A Zullo, G Gallelli… - International journal of …, 2016 - Elsevier
Hepatic ischemia reperfusion injury (IRI) is not only a pathophysiological process involving
the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic …

Antioxidant supplementation in oxidative stress-related diseases: What have we learned from studies on alpha-tocopherol?

FL Meulmeester, J Luo, LG Martens, K Mills… - Antioxidants, 2022 - mdpi.com
Oxidative stress has been proposed as a key contributor to lifestyle-and age-related
diseases. Because free radicals play an important role in various processes such as …

Tocochromanol functions in plants: antioxidation and beyond

J Falk, S Munné-Bosch - Journal of experimental botany, 2010 - academic.oup.com
Tocopherols and tocotrienols, collectively known as tocochromanols, are lipid-soluble
molecules that belong to the group of vitamin E compounds and are essential in the human …

Vitamin E: an overview of major research directions

JM Zingg - Molecular aspects of medicine, 2007 - Elsevier
During the last 90 years since the discovery of vitamin E, research has focused on different
properties of this molecule, the focus often depending on the specific techniques and …

Dynamics of antioxidant action of vitamin E

E Niki, N Noguchi - Accounts of chemical research, 2004 - ACS Publications
Vitamin E is the major lipophilic, radical-scavenging antioxidant in vivo and protects humans
from the oxidative stress mediated by active oxygen and nitrogen species. The mechanisms …

[HTML][HTML] Free radical biology–terminology and critical thinking

A Azzi, KJA Davies, F Kelly - FEBS letters, 2004 - Elsevier
What is an antioxidant? Can one, at a cellular level, speak of direct and indirect
antioxidants? Can oxidative stress be quantified and characterized? What are the oxidant …

Characterization of tocopherol cyclases from higher plants and cyanobacteria. Evolutionary implications for tocopherol synthesis and function

SE Sattler, EB Cahoon, SJ Coughlan… - Plant …, 2003 - academic.oup.com
Tocopherols are lipophilic antioxidants synthesized exclusively by photosynthetic organisms
and collectively constitute vitamin E, an essential nutrient for both humans and animals …

Current knowledge on oxidative stress in hepatic ischemia/reperfusion

M Elias-Miró, MB Jiménez-Castro, J Rodés… - Free radical …, 2013 - Taylor & Francis
Abstract Ischemia/reperfusion (I/R) injury associated with hepatic resections and liver
transplantation remains a serious complication in clinical practice, despite several attempts …

[PDF][PDF] The contemporary role of antioxidant therapy in attenuating liver ischemia‐reperfusion injury: A review

GK Glantzounis, HJ Salacinski, W Yang… - Liver …, 2005 - Wiley Online Library
Oxidative stress is an important factor in many pathological conditions such as inflammation,
cancer, ageing and organ response to ischemia‐reperfusion. Humans have developed a …

Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes

Z Cheng, S Sattler, H Maeda, Y Sakuragi… - The Plant …, 2003 - academic.oup.com
Tocopherols are lipid-soluble compounds synthesized only by photosynthetic eukaryotes
and oxygenic cyanobacteria. The pathway and enzymes for tocopherol synthesis are …