Schizophrenia is a severe psychiatric disorder characterized by emotional, behavioral and
cognitive disturbances, and the treatment of schizophrenia is often complicated by …

Since super-resolution fluorescence microscopic technology breaks the diffraction limit that
has existed for a long time in optical imaging, it can observe the process of synapses formed …

Exercise has been recognized as a beneficial factor for cognitive health, particularly in
relation to the hippocampus, a vital brain region responsible for learning and memory …

Genome-wide association studies (GWASs) have reported multiple single nucleotide
polymorphisms (SNPs) associated with schizophrenia, yet the underlying molecular …

Abstract Background and Hypothesis Cognitive impairment is a hallmark of schizophrenia,
but no effective treatment is available to date. The underlying pathophysiology includes …

Genome-wide gene expression analyses are invaluable tools for studying biological and
disease processes, allowing a hypothesis-free comparison of expression profiles …

Cognitive deficits are a hallmark of schizophrenia, for which no convincing pharmacological
treatment option is currently available. Here, we tested spironolactone as a repurposed …

Recently, hundreds of risk genes associated with psychiatric disorders have been identified.
These are thought to interact with environmental stress factors in precipitating pathological …

The negative influence on the cognitive ability of schizophrenia is one of the issues widely
discussed in recent years. Working memory deficits are thought to be a core cognitive …

Transcription factor 4 (TCF4) is a basic helix-loop-helix transcription factor essential for
neurocognitive development. The aberrations in TCF4 are associated with …