Integrating biomaterials and food biopolymers for cultured meat production

S Ng, M Kurisawa - Acta Biomaterialia, 2021 - Elsevier
Cultured meat has recently achieved mainstream prominence due to the emergence of
societal and industrial interest. In contrast to animal-based production of traditional meat, the …

Mesenchymal stromal cells: from discovery to manufacturing and commercialization

A Mizukami, K Swiech - Stem cells international, 2018 - Wiley Online Library
Over the last decades, mesenchymal stromal cells (MSC) have been the focus of intense
research by academia and industry due to their unique features. MSC can be easily isolated …

Mesenchymal stem cells as a cornerstone in a galaxy of intercellular signals: basis for a new era of medicine

S Fernández-Francos, N Eiro, LA Costa… - International journal of …, 2021 - mdpi.com
Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …

Aging and mesenchymal stem cells: basic concepts, challenges and strategies

M Fraile, N Eiro, LA Costa, A Martín, FJ Vizoso - Biology, 2022 - mdpi.com
Simple Summary Aging and frailty are complex processes implicating multifactorial
mechanisms, which demand for new therapeutic strategies against their devastating effects …

Mesenchymal (Stem) stromal cells based as new therapeutic alternative in inflammatory bowel disease: basic mechanisms, experimental and clinical evidence, and …

N Eiro, M Fraile, A González-Jubete… - International journal of …, 2022 - mdpi.com
Inflammatory bowel diseases (IBD) are an example of chronic diseases affecting 40% of the
population, which involved tissue damage and an inflammatory process not satisfactorily …

Large‐scale expansion of human mesenchymal stem cells

MNFB Hassan, MD Yazid, MHM Yunus… - Stem Cells …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent stem cells with strong immunosuppressive
property that renders them an attractive source of cells for cell therapy. MSCs have been …

Mesenchymal stem cell-based therapy as an alternative to the treatment of acute respiratory distress syndrome: current evidence and future perspectives

S Fernández-Francos, N Eiro… - International journal of …, 2021 - mdpi.com
Acute respiratory distress syndrome (ARDS) represents a current challenge for medicine
due to its incidence, morbidity and mortality and, also, the absence of an optimal treatment …

Influence of microenvironment on mesenchymal stem cell therapeutic potency: from planar culture to microcarriers

AC Tsai, R Jeske, X Chen, X Yuan, Y Li - Frontiers in bioengineering …, 2020 - frontiersin.org
Human mesenchymal stem cells (hMSCs) are a promising candidate in cell therapy as they
exhibit multilineage differentiation, homing to the site of injury, and secretion of trophic …

Overcoming bioprocess bottlenecks in the large-scale expansion of high-quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors

BS Borys, T Dang, T So, L Rohani, T Revay… - Stem Cell Research & …, 2021 - Springer
Background Human induced pluripotent stem cells (hiPSCs) hold enormous promise in
accelerating breakthroughs in understanding human development, drug screening, disease …

Metabolism in human mesenchymal stromal cells: a missing link between hMSC biomanufacturing and therapy?

X Yuan, TM Logan, T Ma - Frontiers in immunology, 2019 - frontiersin.org
Human mesenchymal stem cells (hMSCs) are the most commonly-tested adult stem cells in
cell therapy. While the initial focus for hMSC clinical applications was to exploit their multi …