Vascular and lymphatic malformations represent a challenge for clinicians. The identification
of inherited and somatic mutations in important signaling pathways, including the PI3K …

Objective The management of vascular anomalies is complex and requires a
multidisciplinary team with a combination of medical, surgical, and intervention treatments …

Vascular malformations are inborn errors of vascular morphogenesis and consist of
localized networks of abnormal blood and/or lymphatic vessels with weak endothelial cell …

Significance: Generalized lymphatic anomaly and Gorham–Stout disease are extremely rare
diseases with severe symptoms and poor prognosis. The etiology and clinical presentation …

Optimal pharmacotherapy in pediatric patients with suspected infections requires
understanding and integration of relevant data on the antibiotic, bacterial pathogen, and …

Abstract Background Sturge-Weber syndrome is a rare neurovascular disorder associated
with capillary malformation, seizures, cognitive impairments, and stroke-like episodes …

Transplant-associated thrombotic microangiopathy (TA-TMA) is a fatal posttransplant
complication of hematopoietic stem cell transplantation. We recently reported that survival …

Tregs have the potential to establish long-term immune tolerance in patients recently
diagnosed with type 1 diabetes (T1D) by preserving β cell function. Adoptive transfer of …

Vascular malformations are anomalies in vascular development that portend a significant
risk of hemorrhage, morbidity and mortality. Conventional treatments with surgery …

There has been rising interest in using model‐informed precision dosing to provide
personalized medicine to patients at the bedside. This methodology utilizes population …