Forsythiae Fructus is a traditional Chinese medicine frequently in clinics. It is extensive in the
treatment of various inflammation-related diseases and is renowned as' the holy medicine of …

Abstract Ethnopharmacological relevance Traditional Chinese medicine has gained
significant attention in recent years owing to its multi-component, multi-target, and multi …

Neurodegenerative diseases (NDs) are sporadic maladies that affect patients' lives with
progressive neurological disabilities and reduced quality of life. Neuroinflammation and …

Background Fever is one of the main pathophysiological reactions that occurs during the
acute phase of various diseases. Excessive body temperature can lead to various adverse …

Regulating cardiolipin to maintain mitochondrial homeostasis is a promising strategy for
addressing Parkinson's disease (PD). Through a comprehensive screening and validation …

Intracerebral hemorrhage (ICH), the second most common subtype of stroke, remains a
significant cause of morbidity and mortality worldwide. The pathological mechanism of ICH …

There is currently a shortage of effective therapeutic drugs for Alzheimer's disease (AD),
which is an irreversible neurodegenerative condition. The development of AD is largely …

Phillyrin (PR) and its derivative phillygenol (PG) are major active extracts of the Chinese
medicine Forsythiae Fructus. Lysozyme, an important carrier protein, has a variety of …

The function of white adipose tissue as an energy reservoir is impaired in obesity, leading to
lipid spillover and ectopic lipid deposition. Adipose tissue inflammation can reduce the …

Phillyrin is isolated from the fruit of Forsythia suspensa, and exhibits multiple
pharmacological effects, including anti-tumor, anti-inflammation, and anti-oxidation activities …