Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management

SYC Tong, JS Davis, E Eichenberger… - Clinical microbiology …, 2015 - Am Soc Microbiol
Staphylococcus aureus is a major human pathogen that causes a wide range of clinical
infections. It is a leading cause of bacteremia and infective endocarditis as well as …

Antibiotic resistance: turning evolutionary principles into clinical reality

DI Andersson, NQ Balaban, F Baquero… - FEMS microbiology …, 2020 - academic.oup.com
Antibiotic resistance is one of the major challenges facing modern medicine worldwide. The
past few decades have witnessed rapid progress in our understanding of the multiple factors …

The biogeography of polymicrobial infection

A Stacy, L McNally, SE Darch, SP Brown… - Nature Reviews …, 2016 - nature.com
Microbial communities are spatially organized in both the environment and the human body.
Although patterns exhibited by these communities are described by microbial biogeography …

Comparative genome-scale modelling of Staphylococcus aureus strains identifies strain-specific metabolic capabilities linked to pathogenicity

E Bosi, JM Monk, RK Aziz, M Fondi… - Proceedings of the …, 2016 - National Acad Sciences
Staphylococcus aureus is a preeminent bacterial pathogen capable of colonizing diverse
ecological niches within its human host. We describe here the pangenome of S. aureus …

[HTML][HTML] Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage

K Kitur, D Parker, P Nieto, DS Ahn, TS Cohen… - PLoS …, 2015 - journals.plos.org
Staphylococcus aureus USA300 strains cause a highly inflammatory necrotizing
pneumonia. The virulence of this strain has been attributed to its expression of multiple …

Staphylococcal diversity in atopic dermatitis from an individual to a global scale

SS Kashaf, CP Harkins, C Deming, P Joglekar… - Cell host & …, 2023 - cell.com
Atopic dermatitis (AD) is a multifactorial, chronic relapsing disease associated with genetic
and environmental factors. Among skin microbes, Staphylococcus aureus and …

Origin, evolution, and global transmission of community-acquired Staphylococcus aureus ST8

L Strauß, M Stegger, PE Akpaka… - Proceedings of the …, 2017 - National Acad Sciences
USA300 is a pandemic clonal lineage of hypervirulent, community-acquired, methicillin-
resistant Staphylococcus aureus (CA-MRSA) with specific molecular characteristics. Despite …

[HTML][HTML] Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline

V Da Cunha, MR Davies, PE Douarre… - Nature …, 2014 - nature.com
Abstract Streptococcus agalactiae (Group B Streptococcus, GBS) is a commensal of the
digestive and genitourinary tracts of humans that emerged as the leading cause of bacterial …

Novel staphylococcal cassette chromosome mec (SCCmec) type XIV (5A) and a truncated SCCmec element in SCC composite islands carrying speG in ST5 MRSA …

N Urushibara, MS Aung, M Kawaguchiya… - Journal of …, 2020 - academic.oup.com
Background Staphylococcal cassette chromosome mec (SCC mec) elements are highly
diverse and have been classified into 13 types. The arginine catabolic mobile element …

Changing Characteristics of Staphylococcus aureus Bacteremia: Results From a 21-Year, Prospective, Longitudinal Study

M Souli, F Ruffin, SH Choi, LP Park… - Clinical Infectious …, 2019 - academic.oup.com
Background We conducted a longitudinal study to evaluate changes in the clinical
presentation and epidemiology of Staphylococcus aureus bacteremia (SAB) in an academic …