Effects of omega-3 fatty acids on immune cells

S Gutiérrez, SL Svahn, ME Johansson - International journal of molecular …, 2019 - mdpi.com
Alterations on the immune system caused by omega-3 fatty acids have been described for
30 years. This family of polyunsaturated fatty acids exerts major alterations on the activation …

Nutritional modulation of immune function: analysis of evidence, mechanisms, and clinical relevance

D Wu, ED Lewis, M Pae, SN Meydani - Frontiers in immunology, 2019 - frontiersin.org
It is well-established that the nutritional deficiency or inadequacy can impair immune
functions. Growing evidence suggests that for certain nutrients increased intake above …

Diet, microorganisms and their metabolites, and colon cancer

SJD O'keefe - Nature reviews Gastroenterology & hepatology, 2016 - nature.com
Colorectal cancer is one of the so-called westernized diseases and the second leading
cause of cancer death worldwide. On the basis of global epidemiological and scientific …

Immunomodulatory effects of flavonoids: possible induction of T CD4+ regulatory cells through suppression of mTOR pathway signaling activity

A Hosseinzade, O Sadeghi… - Frontiers in …, 2019 - frontiersin.org
The increasing rate of autoimmune disorders and cancer in recent years has been a
controversial issue in all aspects of prevention, diagnosis, prognosis and treatment. Among …

Animal models to study acute and chronic intestinal inflammation in mammals

JA Jiminez, TC Uwiera, G Douglas Inglis, RRE Uwiera - Gut pathogens, 2015 - Springer
Acute and chronic inflammatory diseases of the intestine impart a significant and negative
impact on the health and well-being of human and non-human mammalian animals …

Omega-3 polyunsaturated fatty acids for the treatment and prevention of colorectal cancer

AJ Cockbain, GJ Toogood, MA Hull - Gut, 2012 - gut.bmj.com
Omega (ω)-3 polyunsaturated fatty acids (PUFAs) are naturally occurring substances that
are well tolerated and have been used extensively for the prevention of cardiovascular …

Narrative Review of n-3 Polyunsaturated Fatty Acid Supplementation upon Immune Functions, Resolution Molecules and Lipid Peroxidation

GP Zaloga - Nutrients, 2021 - mdpi.com
Fish oil supplementation is commonplace in human nutrition and is being used in both
enteral and parenteral formulations during the treatment of patients with a large variety of …

Fish oil attenuates omega-6 polyunsaturated fatty acid-induced dysbiosis and infectious colitis but impairs LPS dephosphorylation activity causing sepsis

S Ghosh, D DeCoffe, K Brown, E Rajendiran, M Estaki… - PloS one, 2013 - journals.plos.org
Clinically, excessive ω-6 polyunsaturated fatty acid (PUFA) and inadequate ω-3 PUFA have
been associated with enhanced risks for developing ulcerative colitis. In rodent models, ω-3 …

Dietary polyunsaturated fatty acids and inflammation: the role of phospholipid biosynthesis

W Raphael, LM Sordillo - International journal of molecular sciences, 2013 - mdpi.com
The composition of fatty acids in the diets of both human and domestic animal species can
regulate inflammation through the biosynthesis of potent lipid mediators. The substrates for …

Mucosal interactions between genetics, diet, and microbiome in inflammatory bowel disease

A Basson, A Trotter, A Rodriguez-Palacios… - Frontiers in …, 2016 - frontiersin.org
Numerous reviews have discussed gut microbiota composition changes during inflammatory
bowel diseases (IBD), particularly Crohn's disease (CD). However, most studies address the …