This review examines how the sympathetic nervous system plays a major role in the
regulation of cardiovascular function over multiple time scales. This is achieved through …

Muscarinic receptors reside in both the atria and ventricles but have a greater density in the
former. 6 They occur more in the endocardium than in the epicardium. Muscarinic receptors …

The cardiac autonomic nervous system consists of 2 branches—the sympathetic and the
parasympathetic systems—that work in a delicately tuned, yet opposing fashion in the heart …

Objectives: This study aimed to investigate the impact of hydroxymethylglutaryl coenzyme A
reductase inhibitor (statin) therapy in patients with advanced heart failure (HF). Background …

There is growing evidence to suggest that many disease states are accompanied by chronic
elevations in sympathetic nerve activity. The present review will specifically focus on central …

The regulation of sympathetic nerve activity in chronic heart failure (CHF) has been an area
of renewed investigation. Understanding the central mechanisms that are responsible for …

Key points A strong correlation between disordered breathing patterns, elevated
sympathetic nerve activity and enhanced chemoreflex sensitivity exists in patients with heart …

OBJECTIVE: To examine the development of subjective symptoms and heart rate variability
(HRV) during motion sickness induced by virtual reality (VR). METHODS: Subjects were 10 …

receptor antisense oligonucleotide administration into the cerebral ventricles reduced
baseline sympathetic nerve activity in rats with CHF while having no effect in normal rats. 36 …

BACKGROUND: Inflammation and oxidative stress have been implicated in the
pathogenesis of atrial fibrillation (AF). Lipid-lowering drugs, particularly statins and fibrates …