TUMOR ANTIGENS RECOGNIZED BY T LYMPHOCYTES Page 1 Annu. Rev, Immunol, 1994.
12:337-65 Copyright © 1994 by Annual Reviews hTc. All rights reserved TUMOR ANTIGENS …

The technological advances occurred in the last few years have led to a great increase in
the number of tumor associated antigens (TAA) that are currently available for clinical …

Tumor-associated, MHC-restricted peptides, recognized by tumor-specific CD8+
lymphocytes, are desirable targets for novel approaches in immunotherapy because of their …

By cDNA expression cloning we have isolated a gene encoding a shared human melanoma
antigen recognized by HLA-A2 restricted autologous and allogenic tumor-infiltrating …

It has been reported previously that antitumor cytolytic T lymphocyte (CTL) clones can be
isolated from blood lymphocytes of HLA-A2 melanoma patients, after stimulation in vitro with …

The cultured T-cell line TIL1200, established from the tumor-infiltrating lymphocytes (TILs) of
a patient with advanced metastatic melanoma, recognized an antigen on most HLA-A2+ …

Four melanoma proteins, MART-1, gp100, tyrosinase, and tyrosinase-related protein-1
(gp75) were evaluated for recognition by HLA-A2-restricted melanoma-specific cytotoxic T …

We recently isolated a cDNA clone that encodes the melanocyte lineage-specific antigen
glycoprotein (gp) 100. Antibodies directed against gp100 are an important tool in the …

Of several thousand peptides presented by the major histocompatibility molecule HLA-A2. 1,
at least nine are recognized by melanoma-specific cytotoxic T lymphocytes (CTLs). Tandem …

T cell defined antigens have now been characterized in a large variety of tumor types, in
both mice and humans. An increasing number of these antigens appear to result from tumor …