Molecular imaging in primary staging of prostate cancer patients: current aspects and future trends
R Manafi-Farid, S Ranjbar, Z Jamshidi Araghi, J Pilz… - Cancers, 2021 - mdpi.com
Simple Summary Accurate primary staging for determining the extent of prostate cancer is
crucial for planning treatment in high-risk patients for distant metastases. Recurrence is still …
crucial for planning treatment in high-risk patients for distant metastases. Recurrence is still …
Diagnostic efficacy of [99mTc]Tc-PSMA SPECT/CT for prostate cancer: a meta-analysis
Q Wang, S Ketteler, S Bagheri, A Ebrahimifard… - BMC cancer, 2024 - Springer
Background Prompt and accurate diagnosis of prostate cancer (PCa) is of paramount
importance for effective treatment planning. While Gallium-68 labeled prostate-specific …
importance for effective treatment planning. While Gallium-68 labeled prostate-specific …
Incorporating PSMA-targeting theranostics into personalized prostate cancer treatment: a multidisciplinary perspective
Recent developments in prostate-specific membrane antigen (PSMA) targeted diagnostic
imaging and therapeutics (theranostics) promise to advance the management of primary …
imaging and therapeutics (theranostics) promise to advance the management of primary …
Prostate-specific membrane antigen-directed imaging and radioguided surgery with single-photon emission computed tomography: state of the art and future outlook
L Filippi, B Palumbo, V Frantellizzi… - Expert Review of …, 2022 - Taylor & Francis
Introduction Prostate-specific membrane antigen (PSMA) has emerged as a highly relevant
target for prostate cancer (PC) diagnosis and therapy. PSMA inhibitors targeting PSMA …
target for prostate cancer (PC) diagnosis and therapy. PSMA inhibitors targeting PSMA …
Tc-99m labeled PSMA-617 as a potential SPECT radiotracer for prostate cancer diagnostics: Complexation optimization and its in vitro/vivo evaluation
K Tachatumvitoon, C Preuksarattanawut… - Bioorganic & Medicinal …, 2025 - Elsevier
Abstract Technetium-99m (Tc-99m) is the most employed radionuclide in nuclear imaging
diagnostics worldwide for many diseases. The ideal physiochemical properties of Tc-99m …
diagnostics worldwide for many diseases. The ideal physiochemical properties of Tc-99m …
Preparation and Biological Evaluation of [99mTc]Tc-CNGU as a PSMA-Targeted Radiotracer for the Imaging of Prostate Cancer
D Xiao, X Duan, Q Gan, X Zhang, J Zhang - Molecules, 2020 - mdpi.com
Prostate-specific membrane antigen (PSMA) is a well-established biological target that is
overexpressed on the surface of prostate cancer lesions. Radionuclide-labeled small …
overexpressed on the surface of prostate cancer lesions. Radionuclide-labeled small …
Bio-Evaluation of 99mTc-Labeled Homodimeric Chalcone Derivative as Amyloid-β-Targeting Probe
Chalcone derivatives have been successfully utilized for a range of biological applications
and can cross the blood–brain barrier easily. β-amyloid-specific bis-chalcone derivative, 6, 9 …
and can cross the blood–brain barrier easily. β-amyloid-specific bis-chalcone derivative, 6, 9 …
[99mTc] Tc-HYNIC-RM2: A potential SPECT probe targeting GRPR expression in prostate cancers
K Vats, A Chakraborty, S Rakshit, A Damle… - Nuclear Medicine and …, 2023 - Elsevier
Introduction Elevated density of gastrin releasing peptide receptors (GRPR) in prostate
cancer has led to exploration of several radiolabeled peptides for imaging and staging of the …
cancer has led to exploration of several radiolabeled peptides for imaging and staging of the …
Comparative Evaluation of Radiochemical and Biological Properties of 131I- and [99mTc]Tc(CO)3-Labeled RGD Analogues Planned to Interact with the αvβ3 …
DV Sobral, LL Fuscaldi, ACR Durante, FF Mendonça… - Pharmaceuticals, 2022 - mdpi.com
Radiolabeled peptides with high specificity for overexpressed receptors in tumor cells hold
great promise for diagnostic and therapeutic applications. In this work, we aimed at …
great promise for diagnostic and therapeutic applications. In this work, we aimed at …
Synthesis of HBED–CC–tris (tert-butyl ester) using a solid phase and a microwave reactor
K Jerzyk, D Kludkiewicz, J Pijarowska-Kruszyna… - Tetrahedron, 2021 - Elsevier
Abstract N, N′-bis-[2-hydroxy-5-(carboxyethyl) benzyl] ethylenediamine-N, N′-diacetic
acid (HBED-CC) belongs to the acyclic, bifunctional complexing compounds used mainly for …
acid (HBED-CC) belongs to the acyclic, bifunctional complexing compounds used mainly for …