Efficacy of bimekizumab and other biologics in moderate to severe plaque psoriasis: a systematic literature review and a network meta-analysis

A Armstrong, K Fahrbach, C Leonardi… - Dermatology and …, 2022 - Springer
Introduction Biologic treatments are increasingly being used in the management of
moderate to severe plaque psoriasis (PSO). Bimekizumab is a selective inhibitor of both …

Association between psoriasis and nonalcoholic fatty liver disease among outpatient US adults

Z Ruan, T Lu, Y Chen, M Yuan, H Yu, R Liu… - JAMA …, 2022 - jamanetwork.com
Importance Recent studies have shown an association between psoriasis and nonalcoholic
fatty liver disease (NAFLD) in US inpatients, but the association is still unclear in the …

Deucravacitinib in the treatment of psoriasis

T Estevinho, AM Lé, T Torres - Journal of Dermatological Treatment, 2023 - Taylor & Francis
Purpose of the article Psoriasis is a chronic, immune-mediated, skin disease with a
significantly negative impact on patients' quality of life. Moderate-to-severe disease often …

Non-alcoholic fatty liver disease (NAFLD) in patients with psoriasis: a review of the hepatic effects of systemic therapies

DMW Balak, S Piaserico, I Kasujee - Psoriasis: Targets and …, 2021 - Taylor & Francis
There is increasing interest in the association between psoriasis and non-alcoholic fatty liver
disease (NAFLD), which is a prevalent liver disease characterized by excessive fat storage …

A route for investigating psoriasis: from the perspective of the pathological mechanisms and therapeutic strategies of cancer

X Wu, Y Ma, L Wang, X Qin - International Journal of Molecular Sciences, 2023 - mdpi.com
Psoriasis is an incurable skin disease that develops in about two-thirds of patients before the
age of 40 and requires lifelong treatment; its pathological mechanisms have not been fully …

Effectiveness of risankizumab in plaque psoriasis with involvement of difficult-to-treat areas: a real-world experience from two referral centers

D Orsini, L Gargiulo, L Ibba… - Journal of …, 2023 - Taylor & Francis
The management of plaque psoriasis that affects difficult-to-treat areas can be challenging.
Biologics have become the treatment of choice for moderate-to-severe plaque psoriasis …

The effectiveness and safety of probiotic supplements for psoriasis: a systematic review and meta‐analysis of randomized controlled trials and preclinical trials

L Zeng, G Yu, Y Wu, W Hao… - Journal of Immunology …, 2021 - Wiley Online Library
Background. Patients with psoriasis need long‐term medication to control their condition.
Recent studies suggest that changing the intestinal flora may be a potential treatment …

Microneedle-assisted percutaneous delivery of methotrexate-loaded nanoparticles enabling sustained anti-inflammatory effects in psoriasis therapy

H Du, J Yang, M Li, Y Xia, Y Li, J Zhu… - Journal of Materials …, 2024 - pubs.rsc.org
Methotrexate (MTX) is one of the first-line drugs used for the treatment of moderate to severe
psoriasis. However, low bioavailability and systemic side effects of traditional oral and …

The impact of psoriasis treatments on the risk of skin Cancer: a narrative review

L Potestio, N Tommasino, G Lauletta, A Salsano… - Advances in …, 2024 - Springer
Several studies have described increased risk ratios of certain types of malignancies in
patients with severe psoriasis. Among these, the lymphoproliferative disorders, including …

Pharmacology of orismilast, a potent and selective PDE4 inhibitor

JI Silverberg, LE French, RB Warren… - Journal of the …, 2023 - Wiley Online Library
Background There remains an unmet need for oral medications that are safe and efficacious
for long‐term management of chronic inflammatory skin diseases (CISD). Inhibition of …