Glycoproteins in animal cells contain a variety of glycan structures that are added co‐and/or
posttranslationally to proteins. Of over 20 different types of sugar–amino acid linkages …

From the earliest days in the field of tumor immunology three questions have been asked: do
cancer cells express tumor-specific antigens, does the immune system recognize these …

Aims De-differentiation and activation of pro-inflammatory pathways are key transitions
vascular smooth muscle cells (SMCs) make during atherogenesis. Here, we explored the …

It is becoming increasingly apparent that cell surface oligosaccharides play pivotal roles as
recognition molecules in a range of cell communication and adhesion processes. Alterations …

The mucin MUC5B has a critical protective function in the normal lung, salivary glands,
esophagus, and gallbladder, and has been reported to be aberrantly expressed in breast …

Aberrant glycosylation and the overexpression of certain carbohydrate moieties is a
consistent feature of cancers, and tumor-associated oligosaccharides are actively …

A deregulation of several MUC genes (MUC1, MUC2, MUC3, MUC5AC, and MUC6) was
previously demonstrated in breast carcinomas. Considering that recently we found the “non …

Simple mucin‐type O‐glycan structures, such as Tn, TF, sialyl‐Tn and Tk antigens, are
among of the most specific human cancer‐associated structures. These antigens are …

The combined and ordered sequential action of glycosidases and glycosyltransferases in
mammalian cell compartments leads to the addition of defined glycans to proteins and lipids …

Mucin glycoproteins are major secreted or membrane‐bound molecules that, in cancer,
show modifications in both the mucin proteins expression and in the O‐glycosylation profile …