Systemic lupus erythematosus, Sjögren's syndrome, and dermatomyositis are systemic
autoimmune diseases that develop after environmental triggering of genetically susceptible …

Cytokines play an important role in host defense against microorganisms. They orchestrate
innate immunity by inducing protective local inflammation and systemic acute phase …

Apoptotic cell clearance facilitates the removal of aged, damaged, infected or dangerous
cells although minimizing perturbation of surrounding tissues, and is a vital process in the …

Objective To examine the role of microRNA‐142‐3p/5p (miR‐142‐3p/5p) in the
development of autoimmunity in patients with systemic lupus erythematosus (SLE). Methods …

Background Recent studies indicate a central role for the IL-23/IL-17 axis in the
pathogenesis of lupus nephritis (LN) but the importance in the context of treatment outcome …

Abstract MicroRNA (miR)‑146a levels are reduced in peripheral blood mononuclear cells of
patients with systemic lupus erythematosus (SLE); however, its function is not well …

The innate immune system is an ancient and primary component system that rapidly reacts
to defend the body against external pathogens. C1 is the initial responder of classical …

PURPOSE: Determination of disease activity of lupus nephritis remains challenging. Since
cytokines play a role as inflammatory mediators extending renal injury, measuring serum …

Background Little is known about the real-time cause-effect relations between IL-6
concentrations and SLE symptoms. Methods A 52-year-old woman with mild SLE activity …

Systemic lupus erythematosus is an autoimmune disease that predominantly affects women
and typically manifests in multiple organs. The damage caused by this disorder is …