Liver fibrosis in non-alcoholic fatty liver disease: from liver biopsy to non-invasive biomarkers in diagnosis and treatment

LJM Heyens, D Busschots, GH Koek, G Robaeys… - Frontiers in …, 2021 - frontiersin.org
An increasing percentage of people have or are at risk to develop non-alcoholic fatty liver
disease (NAFLD) worldwide. NAFLD comprises different stadia going from isolated steatosis …

Oxidative stress is a key modulator in the development of nonalcoholic fatty liver disease

Y Ma, G Lee, SY Heo, YS Roh - Antioxidants, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, and scientific studies consistently report that NAFLD development can be …

Metabolic-associated fatty liver disease (MAFLD): a multi-systemic disease beyond the liver

E Kaya, Y Yilmaz - Journal of clinical and translational …, 2021 - pmc.ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a multisystemic clinical condition that presents
with a wide spectrum of extrahepatic manifestations, such as obesity, type 2 diabetes …

Mechanisms of non-alcoholic fatty liver disease in the metabolic syndrome. A narrative review

L Rinaldi, PC Pafundi, R Galiero, A Caturano… - Antioxidants, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are two different
entities sharing common clinical and physio-pathological features, with insulin resistance …

The effects of probiotics, prebiotics and synbiotics in non-alcoholic fat liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH): A systematic review

RZ Carpi, SM Barbalho, KP Sloan, LF Laurindo… - International journal of …, 2022 - mdpi.com
Modifications in the microbiota caused by environmental and genetic reasons can
unbalance the intestinal homeostasis, deregulating the host's metabolism and immune …

Lipid accumulation product (LAP) index for the diagnosis of nonalcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis

M Ebrahimi, SA Seyedi, SA Nabipoorashrafi… - Lipids in Health and …, 2023 - Springer
Background Lipid accumulation product (LAP) is an index calculated by waist circumference
(WC) and triglyceride (TG), which reflects lipid toxicity. This study aims to investigate the …

UBQLN1 mediates sorafenib resistance through regulating mitochondrial biogenesis and ROS homeostasis by targeting PGC1β in hepatocellular carcinoma

J Xu, L Ji, Y Ruan, Z Wan, Z Lin, S Xia, L Tao… - Signal transduction and …, 2021 - nature.com
The treatment for hepatocellular carcinoma (HCC) is promising in recent years, but still
facing critical challenges. The first targeted therapy, sorafenib, prolonged the overall survival …

[HTML][HTML] European guideline on obesity care in patients with gastrointestinal and liver diseases–Joint ESPEN/UEG guideline

SC Bischoff, R Barazzoni, L Busetto… - Clinical Nutrition, 2022 - Elsevier
Background Patients with chronic gastrointestinal (GI) disease such as inflammatory bowel
disease (IBD), irritable bowel syndrome (IBS), celiac disease, gastroesophageal reflux …

Dietary interventions in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis

V Houttu, S Csader, M Nieuwdorp… - Frontiers in …, 2021 - frontiersin.org
Background: With no approved pharmacotherapy to date, the present therapeutic
cornerstone for non-alcoholic fatty liver diseases (NAFLD) is a lifestyle intervention …

Comparison of NAFLD, MAFLD and MASLD characteristics and mortality outcomes in United States adults

R Song, Z Li, Y Zhang, J Tan, Z Chen - Liver International, 2024 - Wiley Online Library
Abstract Background & Aims Following the classification of metabolic dysfunction‐
associated fatty liver disease (MAFLD), non‐alcoholic fatty liver disease (NAFLD) has …