Endogenous and exogenous sources cause free radical-induced DNA damage in living
organisms by a variety of mechanisms. The highly reactive hydroxyl radical reacts with the …

Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …

Endogenous and exogenous sources cause oxidatively induced DNA damage in living
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …

Troxerutin (TRX) is a flavonoid present in tea, coffee, cereal grains, various fruits and
vegetables have been reported to exhibit radioprotective, antithrombotic, nephro and hepato …

Introduction: Fenugreek is known to possess anti-diabetic as well as antioxidant properties
known to increase with germination. Previous study from our laboratory has reported vitexin …

In irradiated DNA, by the base-to-base and backbone-to-base hole transfer processes, the
hole (ie, the unpaired spin) localizes on the most electropositive base, guanine. Phosphate …

The guanyl radical or neutral guanine radical G (-H)• results from the loss of a hydrogen
atom (H•) or an electron/proton (e–/H+) couple from the guanine structures (G). The guanyl …

Nitric oxide (• NO) is a very effective radiosensitizer of hypoxic mammalian cells. In vivo• NO
may have effects on tumor vasculature and hence on tumor oxygenation and it may also …

Abstract Introduction: Flavonoid Quercetin is a major constituent of fruits and vegetables
which naturally exists in the form of its glycosides, foremost as C3 glycosides. Three …

Oxidative damage to DNA leads to a number of two-electron oxidation products of guanine
such as 8-oxo-7, 8-dihydroguanine (8oxoG). 5-Carboxyamido-5-formamido-2 …