Respiratory syncytial virus (RSV) infections are a constant public health problem, especially
in infants and older adults. Virtually all children will have been infected with RSV by the age …

Messenger RNA (mRNA) vaccines were pivotal in reducing severe acute respiratory
syndrome 2 (SARS-CoV-2) infection burden, yet they have not demonstrated robust …

Whether age-associated defects in T cells impact the immunogenicity and reactogenicity of
mRNA vaccines remains unclear. Using a vaccinated cohort (n= 216), we demonstrated that …

Institutionalized and community-dwelling older adults have been greatly impacted by the
coronavirus disease 2019 (COVID-19) pandemic. 1 Older adults have a higher incidence of …

Data evaluating effectiveness of XBB. 1.5-adapted vaccines against JN. 1-related endpoints
are scarce. This nationwide test-negative case-control study within the US Veterans Affairs …

Adenoviral and mRNA vaccines encoding the viral spike (S) protein have been deployed
globally to contain severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Older …

Background: Our aim was to estimate the rates of not achieving a robust/above-average
humoral response to the COVID-19 mRNA vaccine in people living with HIV (PLWH) who …

The COVID-19 pandemic has shown the potentially devastating impact of novel respiratory
infections worldwide. Insightful data obtained in the last years have shed light on the …

Objectives Elderly are an understudied, high-risk group vulnerable to severe COVID-19. We
comprehensively analyzed the durability of humoral and cellular immune responses after …

Infection persists as one of the leading global causes of morbidity and mortality, with
particular burden at the extremes of age and in populations who are immunocompromised …