The human gastrointestinal tract (GI) harbors a diverse population of microbial life that
continually shapes host pathophysiological responses. Despite readily available abundant …

Aryl hydrocarbon receptor (AhR) is a member of the basic helix–loop–helix–(bHLH)
superfamily of transcription factors, which are associated with cellular responses to …

Tryptamine, a tryptophan-derived monoamine similar to 5-hydroxytryptamine (5-HT), is
produced by gut bacteria and is abundant in human and rodent feces. However, the …

The interaction between host and external environment mainly occurs in the gastrointestinal
tract, where the mucosal barrier has a critical role in many physiologic functions ranging …

The extent to which microbiota alterations define or influence the outcome of metabolic
diseases is still unclear, but the byproducts of microbiota metabolism are known to have an …

The aryl hydrocarbon receptor (AHR) is widely expressed in immune and non-immune cells
of the gut and its activation has been correlated to the outcome of inflammatory bowel …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive
polyarthritis that leads to cartilage and bone damage. Pre-clinical RA is a prolonged state …

Activation of Aryl hydrocarbon receptor (AhR) is involved in the control of intestinal mucosal
homeostasis. Intestinal barrier dysfunction contributes to the development of many intestinal …

Background In food toxicology, there is growing interest in studying the impacts of foodborne
nanoparticles (NPs, originating from food additives, food supplements or food packaging) on …

Intestinal microbiota-mediated aryl hydrocarbon receptor (AhR) activation plays an important
role in host–microbiota interactions and disease development. However, whether AhR …