Role of ATP-small heat shock protein interaction in human diseases
Adenosine triphosphate (ATP) is an important fuel of life for humans and Mycobacterium
species. Its potential role in modulating cellular functions and implications in systemic …
species. Its potential role in modulating cellular functions and implications in systemic …
Combined in silico and in vitro study to reveal the structural insights and nucleotide-binding ability of the transcriptional regulator pehr from the phytopathogen …
The transcriptional regulator PehR regulates the synthesis of the extracellular plant cell wall-
degrading enzyme polygalacturonase, which is essential in the bacterial wilt of plants …
degrading enzyme polygalacturonase, which is essential in the bacterial wilt of plants …
Evidence for inhibition of lysozyme amyloid fibrillization by peptide fragments from human lysozyme: a combined spectroscopy, microscopy, and docking study
Degenerative diseases, such as Alzheimer's and prion diseases, as well as type II diabetes,
have a pathogenesis associated with protein misfolding, which routes with amyloid …
have a pathogenesis associated with protein misfolding, which routes with amyloid …
Interaction of constituents of MDT regimen for leprosy with Mycobacterium leprae HSP18: impact on its structure and function
A Chakraborty, R Ghosh, A Biswas - The FEBS Journal, 2022 - Wiley Online Library
Mycobacterium leprae, the causative organism of leprosy, harbors many antigenic proteins,
and one such protein is the 18‐kDa antigen. This protein belongs to the small heat shock …
and one such protein is the 18‐kDa antigen. This protein belongs to the small heat shock …
Structure, stability and chaperone function of Mycobacterium leprae Heat Shock Protein 18 are differentially affected upon interaction with gold and silver …
A Chakraborty, A Biswas - International journal of biological …, 2020 - Elsevier
Gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs) have several biomedical
applications. However, the effective usage of these two nanoparticles is impeded due to …
applications. However, the effective usage of these two nanoparticles is impeded due to …
The C‐terminal extension of Mycobacterium tuberculosis Hsp16.3 regulates its oligomerization, subunit exchange dynamics and chaperone function
Mycobacterium tuberculosis is a human pathogen that secretes a major immunodominant
antigen, namely Hsp16. 3, throughout the course of infection. Hsp16. 3 belongs to the small …
antigen, namely Hsp16. 3, throughout the course of infection. Hsp16. 3 belongs to the small …
Probing the structure-function relationship of Mycobacterium leprae HSP18 under different UV radiations
Ultraviolet radiation, an effective sterilizing source, rapidly kills the causative organism
(Mycobacterium leprae) of leprosy. But, the reasons behind this quick death are not clearly …
(Mycobacterium leprae) of leprosy. But, the reasons behind this quick death are not clearly …
Conformational perturbation, hydrophobic interactions and oligomeric association are responsible for the enhanced chaperone function of Mycobacterium leprae …
Mycobacterium leprae HSP18 is a small heat shock protein that helps in growth and survival
of Mycobacterium leprae pathogen in host species. Recently, we have shown that its …
of Mycobacterium leprae pathogen in host species. Recently, we have shown that its …
Role of Subunit Exchange and Electrostatic Interactions on the Chaperone Activity of Mycobacterium leprae HSP18
Mycobacterium leprae HSP18, a major immunodominant antigen of M. leprae pathogen, is a
small heat shock protein. Previously, we reported that HSP18 is a molecular chaperone that …
small heat shock protein. Previously, we reported that HSP18 is a molecular chaperone that …
Dodecameric structure of a small heat shock protein from Mycobacterium marinum M
S Bhandari, S Biswas, A Chaudhary… - Proteins: structure …, 2019 - Wiley Online Library
Small heat shock proteins (sHSPs) are ATP‐independent molecular chaperones present
ubiquitously in all kingdoms of life. Their low molecular weight subunits associate to form …
ubiquitously in all kingdoms of life. Their low molecular weight subunits associate to form …