Dysregulation of choline metabolism and therapeutic potential of citicoline in Huntington's disease
KH Chang, ML Cheng, HY Tang, CY Lin, CM Chen - Aging Cell, 2024 - Wiley Online Library
Huntington's disease (HD) is associated with dysregulated choline metabolism, but the
underlying mechanisms remain unclear. This study investigated the expression of key …
underlying mechanisms remain unclear. This study investigated the expression of key …
Potential role of skeletal muscle glycerophosphocholine in response to altered fluid balance in humans: an in vivo nuclear magnetic resonance study
C Baumgartner, P Wolf, H Beiglböck… - American Journal …, 2023 - journals.physiology.org
Many cells adapt to hyperosmolal conditions by upregulation of organic osmolytes to
maintain cell function and integrity. Glycerophosphocholine (GPC), a recognized osmolyte in …
maintain cell function and integrity. Glycerophosphocholine (GPC), a recognized osmolyte in …
A novel insertional allele of the CG18135 gene is associated with severe mutant phenotypes in Drosophila melanogaster
Drosophila melanogaster has been at the forefront of genetic studies and biochemical
modeling for over a century. Yet, the functions of many genes are still unknown, mainly …
modeling for over a century. Yet, the functions of many genes are still unknown, mainly …