The term neuroplasticity encompasses structural and functional modifications of neuronal
connectivity. Abnormal neuroplasticity is involved in various neuropsychiatric diseases, such …

Neurons and glial cells are endowed with membranes that express a rich repertoire of ion
channels, transporters, and receptors. The constant flux of ions across the neuronal and glial …

Under sustained input current of increasing strength neurons eventually stop firing, entering
a depolarization block. This is a robust effect that is not usually explored in experiments or …

Degeneracy, defined as the ability of structurally disparate elements to perform analogous
function, has largely been assessed from the perspective of maintaining robustness of …

Neurodevelopmental disorders (NDDs) that affect cognition, social interaction, and learning,
including autism spectrum disorder (ASD) and intellectual disability (ID), have a strong …

Neurons are highly polarized cells with apparent functional and morphological differences
between dendrites and axon. A critical determinant for the molecular and functional identity …

The maintenance of ion channel homeostasis, or channelostasis, is a complex puzzle in
neurons with extensive dendritic arborization, encompassing a combinatorial diversity of …

Highlights•Different neuron types solve different learning/developmental problems.•Different
neuron types exhibit different dendritic and somatic input–output functions.•A diverse set of …

What are the implications for the existence of subthreshold ion channels, their localization
profiles, and plasticity on local field potentials (LFPs)? Here, we assessed the role of …

An open question within the Bienenstock-Cooper-Munro theory for synaptic modification
concerns the specific mechanism that is responsible for regulating the sliding modification …