Structure of fish Toll-like receptors (TLR) and NOD-like receptors (NLR)

BR Sahoo - International journal of biological macromolecules, 2020 - Elsevier
Innate immunity driven by pattern recognition receptor (PRR) protects the host from invading
pathogens. Aquatic animals like fish where the adaptive immunity is poorly developed …

Review of CRISPR/Cas9 sgRNA design tools

Y Cui, J Xu, M Cheng, X Liao, S Peng - … Sciences: Computational Life …, 2018 - Springer
The adaptive immunity system in bacteria and archaea, Clustered Regularly Interspaced
Short Palindromic Repeats, CRISPR-associate (CRISPR/Cas), has been adapted as a …

Thoroughly remold the localization and signaling pathway of TLR22

J Ji, Z Liao, Y Rao, W Li, C Yang, G Yuan… - Frontiers in …, 2020 - frontiersin.org
TLR22 exists in nearly all the poikilothermic vertebrates and plays a central role in the
initiation of innate immunity and activation of adaptive immunity. TLR22 signaling pathway …

Status of genetic and genomic approaches for delineating biological information and improving aquaculture production of farmed rohu, Labeo rohita (Ham, 1822)

KD Rasal, JK Sundaray - Reviews in Aquaculture, 2020 - Wiley Online Library
Farmed rohu, Labeo rohita, is an economically important freshwater aquaculture species in
south Asia. Consumer preference for this species has driven researchers to develop …

SNPs in the Toll1 receptor of Litopenaeus vannamei are associated with immune response

D Yao, H Su, J Zhu, X Zhao, JJ Aweya, F Wang… - Fish & shellfish …, 2018 - Elsevier
Tolls and Toll-like receptors (TLRs) are important regulators in the innate immune system
and their genetic variations usually affect the host's susceptibility/resistance to pathogen …

Identification and immune-related analysis of SNPs in Litopenaeus vannamei Toll3 receptor

W Wang, JJ Aweya, H Su, X Zhao, M Zhong, Y Zhang - Immunology Letters, 2019 - Elsevier
Tolls and Toll-like receptors (TLRs), as innate immune-recognition receptors that recognize
molecular patterns associated with microbial pathogens, play a critical role in antimicrobial …

Missense mutations involvement in COX-2 structure, and protein-substrate binding affinity: in-silico study

T Zahedi, AH Colagar, H Mahmoodzadeh… - … Nucleotides & Nucleic …, 2021 - Taylor & Francis
Abstract Cyclooxygenase-2 (COX-2) is an inducible inflammatory enzyme, which produces
prostanoids from arachidonic acid. COX-2 overexpression and over-activity can cause …

[PDF][PDF] Identification of Deleterious Nssnps of Interleukin-2 (IL-2) Gene and Its Structural Stability Using Computational Methods

T Sadaf, F Darakhshan - Int J Res, 2018 - academia.edu
Non-synonymous SNPs (nsSNP) found in the coding regions of a gene cause variations in
amino acid residues and are known to influence the function as well as structure of the …

Comparative analysis of guide RNA design tools

P Lavasanifar - 2022 - opus4.kobv.de
Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR), has rapidly come to
the forefront of genome engineering and has revolutionized the field. Today, CRISPR-Cas is …

Structure, function, and potential application of Toll-like receptor 22 from fish

TX Le, MQ Gia, LM Dao… - Science & …, 2022 - stdjns.scienceandtechnology.com.vn
The innate immune system is initiated by the recognition of Pathogen-associated molecular
patterns (PAMPs) through Pattern recognition receptors (PRRs). Among all the identified …