HIV-associated neurocognitive disorder (HAND) is characterized by cognitive and
behavioral deficits in people living with HIV. HAND is still common in patients that take …

As our understanding of changes to the neurological system has improved, it has become
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …

Cocaine abuse increases the incidence of HIV-1-associated neurocognitive disorders. We
have demonstrated that HIV-1 transactivator of transcription (Tat) allosterically modulates …

Background Some evidence suggests that cannabidiol (CBD) has potential to help alleviate
HIV symptoms due to its antioxidant and anti-inflammatory properties. Here we examined …

Viral infections cause damage to various organ systems by inducing organ-specific
symptoms or systemic multi-organ damage. Depending on the infection route and virus type …

HIV-1 selectively disrupts neuronal integrity within specific brain regions, reflecting
differences in viral tropism and/or the regional differences in the vulnerability of distinct …

Human immunodeficiency virus type 1 (HIV-1) is known to provoke microglial immune
responses which likely play a paramount role in the development of chronic …

Human immunodeficiency virus (HIV)-1 transactivator of transcription protein (Tat) is a viral
protein that promotes transcription of the HIV genome and possesses cell-signaling …

Opiate abuse is prevalent among HIV-infected individuals and may exacerbate HIV-
associated age-related neurocognitive disorders. However, the extent to which HIV and …

In the era of combined antiretroviral therapy (cART), human immunodeficiency virus type 1
(HIV-1) is considered a chronic disease with an inflammatory component that specifically …