Kaposiform lymphangiomatosis (KLA) is a life‐threatening rare disease that can cause
substantial morbidity, mortality, and social burdens for patients and their families. Diagnosis …

Abstract The Kasabach-Merritt phenomenon (KMP) in kaposiform hemangioendothelioma
(KHE) is characterized by life-threatening thrombocytopenia and consumptive coagulopathy …

Optimal management of complex vascular anomalies aims to not only treat acute issues,
such as infection or effusion, but also prevent potential future complications and improve …

Background Kaposiform lymphangiomatosis (KLA) is a complex lymphatic anomaly
involving most commonly the mediastinum, lung, skin and bones with few effective …

Kaposiform lymphangiomatosis is an uncommon generalized lymphatic anomaly with
distinctive clinical, radiologic, histopathologic, and molecular findings. Herein, we document …

Background: Generalized lymphatic anomaly (GLA), Gorham-Stout disease (GSD),
kaposiform lymphangiomatosis (KLA), and central conducting lymphatic anomaly (CCLA) …

Kaposiform lymphangiomatosis (KLA) is a very rare form of generalized lymphatic anomaly,
consisting of a diffuse proliferation of abnormal, dilated lymphatics, and small fascicles of …

Kaposiform hemangioendotheliomas (KHEs) are vascular tumors that are considered
borderline or locally aggressive and may lead to lethal outcomes. Traditional therapies, such …

Sirolimus and everolimus have been widely used in children. These mammalian target of
rapamycin (mTOR) inhibitors have shown excellent efficacy not only in organ transplant …

Targeted medical therapies for the treatment of vascular malformations is an exciting and
evolving area of research. As the identification of specific causative genetic mutations …