Tasmanian devil cathelicidins exhibit anticancer activity against Devil Facial Tumour Disease (DFTD) cells
Abstract The Tasmanian devil (Sarcophilus harrisii) is endangered due to the spread of
Devil Facial Tumour Disease (DFTD), a contagious cancer with no current treatment options …
Devil Facial Tumour Disease (DFTD), a contagious cancer with no current treatment options …
A human adenovirus encoding IFN-γ can transduce Tasmanian devil facial tumour cells and upregulate MHC-I
AN Kayigwe, J M. Darby, AB Lyons… - Journal of General …, 2022 - microbiologyresearch.org
The devil facial tumour disease (DFTD) has led to a massive decline in the wild Tasmanian
devil (Sarcophilus harrisii) population. The disease is caused by two independent devil …
devil (Sarcophilus harrisii) population. The disease is caused by two independent devil …
Pharmaceutics for free-ranging wildlife: case studies to illustrate considerations and future prospects
A McDowell - International Journal of Pharmaceutics, 2022 - Elsevier
Wildlife medicine is a specialised division of veterinary medicine that is concerned with
patients that are physiologically very diverse with similarly diverse life histories. The …
patients that are physiologically very diverse with similarly diverse life histories. The …
Reinforcements in the face of ongoing threats: a case study from a critically small carnivore population
Reinforcements are a well‐established tool for alleviating small population pressures of
inbreeding and genetic diversity loss. Some small populations also suffer from specific …
inbreeding and genetic diversity loss. Some small populations also suffer from specific …
Mesenchymal plasticity of devil facial tumour cells during in vivo vaccine and immunotherapy trials
AL Patchett, C Tovar, NB Blackburn… - Immunology and cell …, 2021 - Wiley Online Library
Immune evasion is critical to the growth and survival of cancer cells. This is especially
pertinent to transmissible cancers, which evade immune detection across genetically …
pertinent to transmissible cancers, which evade immune detection across genetically …
Evaluation of oral baits and distribution methods for Tasmanian devils (Sarcophilus harrisii)
S Dempsey, RJ Pye, AT Gilbert… - Wildlife …, 2022 - CSIRO Publishing
Context Diseases are increasingly contributing to wildlife population declines. Tasmanian
devil (Sarcophilus harrisii) populations have locally declined by 82%, largely owing to the …
devil (Sarcophilus harrisii) populations have locally declined by 82%, largely owing to the …
Automated Analysis of PD1 and PDL1 Expression in Lymph Nodes and the Microenvironment of Transmissible Tumors in Tasmanian Devils
ABSTRACT The wild Tasmanian devil (Sarcophilus harrisii) population has suffered a
devastating decline due to two clonal transmissible cancers. The first devil facial tumor 1 …
devastating decline due to two clonal transmissible cancers. The first devil facial tumor 1 …
9 Perspective–Whole genome assemblies, devils and disease
A theme that has been emerging over the past decade in conservation is the creation and
use of reference genomes to inform conservation actions. These whole genome assemblies …
use of reference genomes to inform conservation actions. These whole genome assemblies …
CIITA induces expression of MHC-I and MHC-II in transmissible cancers
Abstract MHC-I and MHC-II molecules are critical components of antigen presentation and T
cell immunity to pathogens and cancer. The two monoclonal transmissible devil facial …
cell immunity to pathogens and cancer. The two monoclonal transmissible devil facial …
Development of synthetic immunological tools for Tasmanian devil research
AJ De Luca - 2022 - figshare.utas.edu.au
The Tasmanian devil (Sarcophilus harrisii) is the world ‚ÄövÑv¥ s largest extant carnivorous
marsupial. The wild population of devils has been decimated by two transmissible cancers …
marsupial. The wild population of devils has been decimated by two transmissible cancers …