The clinical symptoms of Parkinson's disease

S Sveinbjornsdottir - Journal of neurochemistry, 2016 - Wiley Online Library
In this review, the clinical features of Parkinson's disease, both motor and non‐motor, are
described in the context of the progression of the disease. Also briefly discussed are the …

Depression in patients with Parkinson's disease: current understanding of its neurobiology and implications for treatment

S Prange, H Klinger, C Laurencin, T Danaila… - Drugs & Aging, 2022 - Springer
Depression is one of the most frequent and burdensome non-motor symptoms in
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …

The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease

P Barone, A Antonini, C Colosimo… - … : official journal of the …, 2009 - Wiley Online Library
We performed a multicenter survey using a semistructured interview in 1,072 consecutive
patients with Parkinson's disease (PD) enrolled during 12 months in 55 Italian centers to …

Falls and freezing of gait in Parkinson's disease: a review of two interconnected, episodic phenomena

BR Bloem, JM Hausdorff, JE Visser… - … : official journal of the …, 2004 - Wiley Online Library
Falls and freezing of gait are two “episodic” phenomena that are common in Parkinson's
disease. Both symptoms are often incapacitating for affected patients, as the associated …

A systematic review of prevalence studies of depression in Parkinson's disease

JSAM Reijnders, U Ehrt, WEJ Weber… - Movement …, 2008 - Wiley Online Library
Prevalence rates of depressive disorders in Parkinson's disease (PD) vary widely across
studies, ranging from 2.7% to more than 90%. The aim of this systematic review was to …

Clinical and health services relationships between major depression, depressive symptoms, and general medical illness

WJ Katon - Biological psychiatry, 2003 - Elsevier
Patients with chronic medical illness have a high prevalence of major depressive illness.
Major depression may decrease the ability to habituate to the aversive symptoms of chronic …

Sydney multicenter study of Parkinson's disease: Non‐L‐dopa–responsive problems dominate at 15 years

MA Hely, JGL Morris, WGJ Reid… - … : official journal of the …, 2005 - Wiley Online Library
One‐third of the 149 people recruited 15 to 18 years ago in the Sydney Multicenter Study of
Parkinson's disease have survived. The original study compared low‐dose levodopa with …

Gait dynamics in Parkinson's disease: common and distinct behavior among stride length, gait variability, and fractal-like scaling

JM Hausdorff - Chaos: An Interdisciplinary Journal of Nonlinear …, 2009 - pubs.aip.org
Parkinson's disease (PD) is a common, debilitating neurodegenerative disease. Gait
disturbances are a frequent cause of disability and impairment for patients with PD. This …

Neuropsychiatric symptoms in Parkinson's disease

D Aarsland, L Marsh, A Schrag - Movement disorders: official …, 2009 - Wiley Online Library
Neuropsychiatric symptoms are common in Parkinson's disease, even at the earliest stages,
and have important consequences for quality of life and daily functioning, are associated …

Depression rating scales in Parkinson's disease: critique and recommendations

A Schrag, P Barone, RG Brown… - Movement …, 2007 - Wiley Online Library
Depression is a common comorbid condition in Parkinson's disease (PD) and a major
contributor to poor quality of life and disability. However, depression can be difficult to …