Cancer testis antigens (CTA) are a large family of tumor-associated antigens expressed in
human tumors of different histological origin, but not in normal tissues except for testis and …

Primary testicular lymphoma (PTL) is a rare, clinically aggressive form of extranodal
lymphoma. The vast majority of cases are histologically diffuse large B-cell lymphoma, but …

Mutations in the germline generates all evolutionary genetic variation and is a cause of
genetic disease. Parental age is the primary determinant of the number of new germline …

Quercetin is a dietary polyphenolic compound with potentially beneficial effects on health.
Claims that quercetin has biological effects are based mainly on in vitro studies with …

A synergistic effect of P-glycoprotein (P-gp)/Abcb1a and breast cancer resistance protein
(Bcrp)/Abcg2 was reported to limit the brain penetration of their common substrates. This …

Melanoma antigen (MAGE) genes are conserved in all eukaryotes and encode for proteins
sharing a common MAGE homology domain. Although only a single MAGE gene exists in …

BACKGROUND The transmembrane ATP-binding cassette (ABC) transporters actively efflux
an array of clinically relevant compounds across biological barriers, and modulate …

Cancer/testis‐associated genes (CTAs) are a subgroup of tumor antigens with a restricted
expression in testis and malignancies. During the last decade, many of these …

The blood‐testis barrier (BTB) in mammals, such as rats, is composed of the tight junction
(TJ), the basal ectoplasmic specialization (basal ES), the basal tubulobulbar complex (basal …

Islet transplantation has shown promise as a curative therapy for type 1 diabetes (T1D).
However, the side effects of systemic immunosuppression and limited long‐term viability of …