Anti-glomerular basement membrane (anti-GBM) disease is a rare life-threatening small-
vessel vasculitis that typically affects the capillaries of kidneys and lungs, with most of …

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) are a group of
multisystemic autoimmune diseases characterized by necrotizing inflammation of small …

Introduction In the 330-patient ADVOCATE trial of avacopan for the treatment of
antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis, in which 81% of …

Background Acute kidney injury (AKI) is a common and severe complication of anti-
neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV), potentially leading to …

Objective. We have recently described the frequency of Bowman's capsule (BC) rupture in a
considerable subset of patients with antineutrophil cytoplasmic antibody (ANCA)-associated …

We previously showed that the rupture of Bowman's capsule (BC) promotes the progression
of crescentic glomerulonephritis by enhancing the entry of CD8+ T cells into the glomeruli. In …

Eosinophilic granulomatosis with polyangiitis (EGPA) is a necrotizing vasculitis, which
typically affects small-to medium-sized blood vessels. It is characterized by the presence of …

Background and objective Lupus nephritis is one of the most severe manifestations of
systemic lupus erythematosus. The clinical and prognostic significance of Bowman's …

Bowman's capsule rupture was first reported more than 30 years ago and only few case
reports described its presence in diseased kidneys to date. 1 We read with great interest the …

Background Renal involvement is a common and severe complication of ANCA
(antineutrophil cytoplasmic antibody) associated vasculitis (AAV) potentially resulting in a …