Type I interferons (IFNs) play essential roles in establishing and modulating host defense
against microbial infection via induction of IFN-stimulated genes (ISGs) through Janus …

It is increasingly clear that long non-coding RNAs (lncRNAs) regulate a variety biological
responses, and that they do so by a diverse range of mechanisms. In the field of …

Despite significant improvements during the past 3 decades, cardiovascular disease
remains a leading worldwide health epidemic. The recent identification of a fascinating …

Long noncoding RNAs (lncRNAs) are pivotal regulators of genome structure and gene
expression. LncRNAs can directly interact with chromatin-modifying enzymes and …

Increasing evidence has indicated that plenty of lncRNAs play important roles in many
critical biological processes. Developing powerful computational models to construct …

Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related
death worldwide, and the biology of this cancer remains poorly understood. Recent …

Background Colorectal cancer (CRC) arises in a multistep molecular network process,
which is from either discrete genetic perturbation or epigenetic dysregulation. The long non …

Background Mounting evidence indicates that long noncoding RNAs (lncRNAs) could play a
pivotal role in cancer biology. However, the overall biological role and clinical significance of …

Accumulating experimental studies have indicated that lncRNAs play important roles in
various critical biological process and their alterations and dysregulations have been …

Cervical cancer contributed the second highest number of deaths in female cancers,
exceeded only by breast cancer, carrying high risks of morbidity and mortality. There was a …