The drug-induced, reversible coma of anaesthesia requires three clinical outcomes:
unconsciousness, immobility, and the control of autonomic nervous system (ANS) responses …

Introduction Head and neck free flap reconstruction requires multidisciplinary and
coordinated care in the perioperative setting to ensure safe recovery and success. Several …

Background Although opioids play a critical role in the management of cancer pain, the
ongoing opioid epidemic has raised concerns regarding their persistent use and abuse. We …

Oral pain due to cancer and associated treatments is common. The prevalence and severity
of oral cancer is high. Painful oral mucositis develops in head and neck cancer patients …

Objective Deaths from prescription opioid overdose have quadrupled in the past 15 years,
and no studies have evaluated appropriate opioid prescribing after cardiac surgery. The aim …

Importance An increase in narcotic prescription patterns has contributed to the current opioid
epidemic in the United States. Opioid-sparing perioperative analgesia represents a means …

Context The prevalence of chronic pain in cancer survivors is double that of the general US
population. Opioids have been the foundation of cancer pain management for decades; …

Purpose Opioids are a mainstay of cancer pain management; however, patients with
metastatic cancer are often excluded from studies, leading to a lack of evidence on whether …

Objective Postoperative pain after head and neck cancer surgery is commonly treated with
opioids, which are associated with considerable side effects. The objective of this study is to …

The perioperative care of adult patients undergoing free tissue transfer during head and
neck surgical (microvascular) reconstruction is inconsistent across practitioners and …