[HTML][HTML] Oncogenic effects of HIV-1 proteins, mechanisms behind

M Isaguliants, E Bayurova, D Avdoshina… - Cancers, 2021 - mdpi.com
Simple Summary People living with human immunodeficiency virus type 1 (HIV-1)(PLWH)
are at increased risk of developing cancer despite successful antiretroviral therapy (ART) …

[HTML][HTML] A tale of two viruses: immunological insights into HCV/HIV coinfection

ST Gobran, P Ancuta, NH Shoukry - Frontiers in immunology, 2021 - frontiersin.org
Nearly 2.3 million individuals worldwide are coinfected with human immunodeficiency virus
(HIV) and hepatitis C virus (HCV). Odds of HCV infection are six times higher in people living …

Positive-sense RNA viruses reveal the complexity and dynamics of the cellular and viral epitranscriptomes during infection

W McIntyre, R Netzband, G Bonenfant… - Nucleic Acids …, 2018 - academic.oup.com
More than 140 post-transcriptional modifications (PTMs) are known to decorate cellular
RNAs, but their incidence, identity and significance in viral RNA are still largely unknown …

[HTML][HTML] The role of MDM2–p53 axis dysfunction in the hepatocellular carcinoma transformation

H Cao, X Chen, Z Wang, L Wang, Q Xia… - Cell Death Discovery, 2020 - nature.com
Liver cancer is the second most frequent cause of cancer-related death globally. The main
histological subtype is hepatocellular carcinoma (HCC), which is derived from hepatocytes …

The assessment of selected MiRNAs profile in HIV, HBV, HCV, HIV/HCV, HIV/HBV Co-infection and elite controllers for determination of biomarker

S Yousefpouran, S Mostafaei, PV Manesh… - Microbial …, 2020 - Elsevier
Background The emerging relationship between microRNAs (miRNA) and viral-control is a
topic of interest in the field of HIV. Host-genome might play an important role in the control of …

[HTML][HTML] Nef-induced CCL2 expression contributes to HIV/SIV brain invasion and neuronal dysfunction

MH Lehmann, JM Lehmann, V Erfle - Frontiers in immunology, 2019 - frontiersin.org
CC motif chemokine ligand 2 (CCL2) is a chemoattractant for leukocytes including
monocytes, T cells, and natural killer cells and it plays an important role in maintaining the …

[HTML][HTML] Alcohol metabolism potentiates HIV-induced hepatotoxicity: contribution to end-stage liver disease

M Ganesan, M New-Aaron, RS Dagur, E Makarov… - Biomolecules, 2019 - mdpi.com
In an era of improved survival due to modern antiretroviral therapy, liver disease has
become a major cause of morbidity and mortality, resulting in death in 15–17% of human …

[HTML][HTML] Characterization of Nef expression in different brain regions of SIV-infected macaques

SS Yarandi, JA Robinson, S Vakili, M Donadoni… - PLoS …, 2020 - journals.plos.org
Objective HIV-associated CNS dysfunction is a significant problem among people with HIV
(PWH), who now live longer due to viral suppression from combined anti-retroviral therapy …

Virological Mechanisms in the Coinfection between HIV and HCV

MC Liberto, E Zicca, G Pavia, A Quirino… - Mediators of …, 2015 - Wiley Online Library
Due to shared transmission routes, coinfection with Hepatitis C Virus (HCV) is common in
patients infected by Human Immunodeficiency Virus (HIV). The immune‐pathogenesis of …

[HTML][HTML] Exosomes are unlikely involved in intercellular Nef transfer

X Luo, Y Fan, IW Park, JJ He - PloS one, 2015 - journals.plos.org
HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis. Several recent
studies including ours have demonstrated that Nef can be transferred to neighboring cells …