Aging causes skeletal muscle atrophy, and myofiber loss can be a critical component of this
process. In 1989, Rosenberg emphasized the importance of the loss of skeletal muscle …

The horse was domesticated only 5.5 KYA, thousands of years after dogs, cattle, pigs,
sheep, and goats. The horse nonetheless represents the domestic animal that most …

Intense selective pressures applied over short evolutionary time have resulted in
homogeneity within, but substantial variation among, horse breeds. Utilizing this population …

Selective breeding for speed in the racehorse has resulted in an unusually high frequency of
the C-variant (g. 66493737C/T) at the myostatin gene (MSTN) in cohorts of the …

The application of new technologies for gene editing in horses may allow the generation of
improved sportive individuals. Here, we aimed to knock out the myostatin gene (MSTN), a …

A horse's success on the racetrack is determined by genetics, training and nutrition, and
their translation into physical traits such as speed, endurance and muscle strength …

Myostatin is a member of the transforming growth factor-β family with a key role in inhibition
of muscle growth by negative regulation of both myoblast proliferation and differentiation …

The proliferation and differentiation of skeletal muscle satellite cells (SCs) are necessary for
the development of mature skeletal muscle. Leucine (Leu) is both an essential amino acid …

Background A single bout of exercise induces changes in gene expression in skeletal
muscle. Regular exercise results in an adaptive response involving changes in muscle …

Background Although harness racing is of high economic importance to the global equine
industry, significant genomic resources have yet to be applied to mapping harness racing …