Principles of fluid management and stewardship in septic shock: it is time to consider the four D's and the four phases of fluid therapy
MLNG Malbrain, N Van Regenmortel, B Saugel… - Annals of intensive …, 2018 - Springer
In patients with septic shock, the administration of fluids during initial hemodynamic
resuscitation remains a major therapeutic challenge. We are faced with many open …
resuscitation remains a major therapeutic challenge. We are faced with many open …
Acute kidney injury in sepsis
Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous
presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU …
presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU …
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …
Balanced crystalloids versus saline in critically ill adults
Background Both balanced crystalloids and saline are used for intravenous fluid
administration in critically ill adults, but it is not known which results in better clinical …
administration in critically ill adults, but it is not known which results in better clinical …
Balanced crystalloids versus saline in noncritically ill adults
Background Comparative clinical effects of balanced crystalloids and saline are uncertain,
particularly in noncritically ill patients cared for outside an intensive care unit (ICU). Methods …
particularly in noncritically ill patients cared for outside an intensive care unit (ICU). Methods …
[HTML][HTML] Focus: Death: Organ dysfunction in sepsis: An ominous trajectory from infection to death
C Caraballo, F Jaimes - The Yale journal of biology and medicine, 2019 - ncbi.nlm.nih.gov
Sepsis is a highly complex and lethal syndrome with highly heterogeneous clinical
manifestations that makes it difficult to detect and treat. It is also one of the major and most …
manifestations that makes it difficult to detect and treat. It is also one of the major and most …
Sepsis-associated acute kidney injury
CL Manrique-Caballero… - Critical Care …, 2021 - criticalcare.theclinics.com
Sepsis-associated acute kidney injury (S-AKI) is a common, life-threatening complication in
hospitalized and critically ill patients. S-AKI increases in-hospital mortality 6-fold to 8-fold, 1 …
hospitalized and critically ill patients. S-AKI increases in-hospital mortality 6-fold to 8-fold, 1 …
Prevention of acute kidney injury and protection of renal function in the intensive care unit: update 2017: Expert opinion of the Working Group on Prevention, AKI …
M Joannidis, W Druml, LG Forni, ABJ Groeneveld… - Intensive care …, 2017 - Springer
Background Acute kidney injury (AKI) in the intensive care unit is associated with significant
mortality and morbidity. Objectives To determine and update previous recommendations for …
mortality and morbidity. Objectives To determine and update previous recommendations for …
Balanced crystalloids versus saline in critically ill adults—a systematic review with meta-analysis
Background The comparative efficacy and safety of balanced crystalloid solutions and saline
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …
Intravenous fluid therapy in critically ill adults
Intravenous fluid therapy is one of the most common interventions in acutely ill patients.
Each day, over 20% of patients in intensive care units (ICUs) receive intravenous fluid …
Each day, over 20% of patients in intensive care units (ICUs) receive intravenous fluid …