Lignans and Neolignans: Plant secondary metabolites as a reservoir of biologically active substances

F Zálešák, DJYD Bon, J Pospíšil - Pharmacological Research, 2019 - Elsevier
Lignans and neolignans are plant secondary metabolites derived from the oxidative
coupling of phenylpropanoids. Biological activity of these phenolic compounds ranges from …

Molecular mechanism of down-regulating adipogenic transcription factors in 3T3-L1 adipocyte cells by bioactive anti-adipogenic compounds

A Guru, PK Issac, M Velayutham, NT Saraswathi… - Molecular Biology …, 2021 - Springer
Obesity is growing at an alarming rate, which is characterized by increased adipose tissue. It
increases the probability of many health complications, such as diabetes, arthritis, cardiac …

Evaluation of the anti-diabetic activity of some common herbs and spices: providing new insights with inverse virtual screening

ASP Pereira, AJ Banegas-Luna, J Peña-García… - Molecules, 2019 - mdpi.com
Culinary herbs and spices are widely used as a traditional medicine in the treatment of
diabetes and its complications, and there are several scientific studies in the literature …

[HTML][HTML] Natural products: regulating glucose metabolism and improving insulin resistance

FSA Saadeldeen, Y Niu, H Wang, L Zhou… - Food science and …, 2020 - Elsevier
Compounds with regulating glucose metabolism and improving insulin resistance (IR)
activity are abundant in nature and can be obtained from several sources. They have high …

Dexamethasone-induced mitochondrial dysfunction and insulin resistance-study in 3T3-L1 adipocytes and mitochondria isolated from mouse liver

G Luan, G Li, X Ma, Y Jin, N Hu, J Li, Z Wang, H Wang - Molecules, 2019 - mdpi.com
Dexamethasone is a glucocorticoid analog, which is reported to induce insulin resistance
and to exacerbate diabetic symptoms. In this study, we investigated the association between …

Kaempferide improves glycolipid metabolism disorder by activating PPARγ in high-fat-diet-fed mice

H Tang, Q Zeng, T Tang, Y Wei, P Pu - Life sciences, 2021 - Elsevier
Abstract Aims Kaempferide (Ka, 3, 5, 7-trihydroxy-4′-methoxyflavone), an active ingredient
of Tagetes erecta L., has been demonstrated to possess many pharmacological effects …

Flavonoid glycosides from fenugreek seeds regulate glycolipid metabolism by improving mitochondrial function in 3T3-L1 adipocytes in vitro

G Luan, Y Wang, Z Wang, W Zhou, N Hu… - Journal of agricultural …, 2018 - ACS Publications
Fenugreek is a well known annual herb widely used in both medicine and food. Four
flavonoid glycosides have been separated from fenugreek seeds in our previous study. In …

Oroxin A from Oroxylum indicum prevents the progression from prediabetes to diabetes in streptozotocin and high-fat diet induced mice

W Sun, B Zhang, X Yu, C Zhuang, X Li, J Sun, Y Xing… - Phytomedicine, 2018 - Elsevier
Abstract Background Oroxylum indicum (L.) Kurz (Bignoniaceae) has been widely used for
the treatment of respiratory infections and gastrointestinal disorders. Our previous study …

The Protective Effect of Myristica fragrans Houtt. Extracts Against Obesity and Inflammation by Regulating Free Fatty Acids Metabolism in Nonalcoholic Fatty Liver …

W Zhao, F Song, D Hu, H Chen, Q Zhai, W Lu, J Zhao… - Nutrients, 2020 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a disorder characterized by the excess
accumulation of fat in the hepatocytes. It is commonly associated with severe obesity and …

Soluble individual metal atoms and ultrasmall clusters catalyze key synthetic steps of a natural product synthesis

S Rodríguez-Nuévalos, M Espinosa… - Communications …, 2024 - nature.com
Metal individual atoms and few-atom clusters show extraordinary catalytic properties for a
variety of organic reactions, however, their implementation in total synthesis of complex …