Concussion is confusing us all

DJ Sharp, PO Jenkins - Practical neurology, 2015 - pn.bmj.com
It is time to stop using the term concussion as it has no clear definition and no pathological
meaning. This confusion is increasingly problematic as the management of …

Antioxidant therapies in traumatic brain injury

V Di Pietro, KM Yakoub, G Caruso, G Lazzarino… - Antioxidants, 2020 - mdpi.com
Due to a multiplicity of causes provoking traumatic brain injury (TBI), TBI is a highly
heterogeneous pathology, characterized by high mortality and disability rates. TBI is an …

Gait impairment in traumatic brain injury: A systematic review

A Dever, D Powell, L Graham, R Mason, J Das… - Sensors, 2022 - mdpi.com
Introduction: Gait impairment occurs across the spectrum of traumatic brain injury (TBI); from
mild (mTBI) to moderate (modTBI), to severe (sevTBI). Recent evidence suggests that …

Decompressive craniectomy following traumatic brain injury: developing the evidence base

AG Kolias, H Adams, I Timofeev… - British journal of …, 2016 - Taylor & Francis
In the context of traumatic brain injury (TBI), decompressive craniectomy (DC) is used as part
of tiered therapeutic protocols for patients with intracranial hypertension (secondary or …

Analysis of the role of CX3CL1 (Fractalkine) and its receptor CX3CR1 in traumatic brain and spinal cord injury: insight into recent advances in actions of …

ŁA Poniatowski, P Wojdasiewicz, M Krawczyk… - Molecular …, 2017 - Springer
Abstract CX3CL1 (fractalkine) is the only member of the CX3C (delta) subfamily of
chemokines which is unique and combines the properties of both chemoattractant and …

Notch-1 Signaling Regulates Microglia Activation via NF-κB Pathway after Hypoxic Exposure In Vivo and In Vitro

L Yao, EM Kan, C Kaur, ST Dheen, A Hao, J Lu… - PloS one, 2013 - journals.plos.org
Neuroinflammation mediated by the activated microglia is suggested to play a pivotal role in
the pathogenesis of hypoxic brain injury; however, the underlying mechanism of microglia …

Glucose metabolism following human traumatic brain injury: methods of assessment and pathophysiological findings

I Jalloh, KLH Carpenter, A Helmy, TA Carpenter… - Metabolic brain …, 2015 - Springer
The pathophysiology of traumatic brain (TBI) injury involves changes to glucose uptake into
the brain and its subsequent metabolism. We review the methods used to study cerebral …

Metabolic imaging of energy metabolism in traumatic brain injury using hyperpolarized [1-13C]pyruvate

SJ DeVience, X Lu, J Proctor, P Rangghran… - Scientific reports, 2017 - nature.com
Traumatic brain injury (TBI) is known to cause perturbations in the energy metabolism of the
brain, but current tests of metabolic activity are only indirect markers of energy use or are …

Acute inflammatory biomarker responses to diffuse traumatic brain injury in the rat monitored by a novel microdialysis technique

F Clausen, N Marklund, L Hillered - Journal of neurotrauma, 2019 - liebertpub.com
Neuroinflammation is a major contributor to the progressive brain injury process induced by
traumatic brain injury (TBI), and may play an important role in the pathophysiology of axonal …

Intraspinal pressure and spinal cord perfusion pressure after spinal cord injury: an observational study

GV Varsos, MC Werndle, ZH Czosnyka… - … of Neurosurgery: Spine, 2015 - thejns.org
OBJECT In contrast to intracranial pressure (ICP) in traumatic brain injury (TBI), intraspinal
pressure (ISP) after traumatic spinal cord injury (TSCI) has not received the same attention …